ReviewBasic and clinical neuroscience
Comparing the Efficiency of Two Treatment Methods of Hydrocephalus: Shunt Implantation and Endoscopic Third Ventriculostomy.
Review in Basic and clinical neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.
- Pineal Region Gliomas: A Systematic Review of Clinical Features and Treatment Outcomes.Anticancer research · 2022Pooled it
- PITCH (pediatric infratentorial tumors - hydrocephalus-related complications) registry study design: observational, prospective, multicenter study evaluating the number of surgeries associated with the treatment of hydrocephalus secondary to infratentorial tumors in childhood and adolescence.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Observational
- Feasibility Study on Inflammasome Proteins as Biomarkers in the Cerebrospinal Fluid of Pediatric Patients with Hydrocephalus Due to Intraventricular Hemorrhage.Biomolecules · 2025Article
- Tension hydrothorax due to delayed and spontaneous supradiaphragmatic and intrathoracic migration of ventriculoperitoneal shunt catheter in pediatric patient: a rare complication with exhaustive literature review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Review
- Article
- Optimization of number and range of shunt valve performance levels in infant hydrocephalus: a machine learning analysis.Frontiers in bioengineering and biotechnology · 2024Article
- The Inhibition of Mitogen-Activated Protein Kinases (MAPKs) and NF-κB Underlies the Neuroprotective Capacity of a Cinnamon/Curcumin/Turmeric Spice Blend in Aβ-Exposed THP-1 Cells.Molecules (Basel, Switzerland) · 2023Article
- Why Intracranial Compliance Is Not Utilized as a Common Practical Tool in Clinical Practice.Biomedicines · 2023Review
- Posterior fossa choroidplexus papilloma in the pediatric population: case series and literature review.Arquivos de neuro-psiquiatria · 2023Review
- Long-term recovery behavior of brain tissue in hydrocephalus patients after shunting.Communications biology · 2022Article
- Cerebrospinal fluid hydrocephalus shunting: cisterna magna, ventricular frontal, ventricular occipital.Neurosurgical review · 2022Review
- Is Shunt Location a Risk Factor for the Development ofIranian journal of medical sciences · 2022Article
- A New Definition for Intracranial Compliance to Evaluate Adult Hydrocephalus After Shunting.Frontiers in bioengineering and biotechnology · 2022Article
- Spontaneous third ventriculostomy in patients undergoing fetal surgery for myelomeningocele correction.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Sinking skin flap syndrome in a patient with bone resorption after cranioplasty and ventriculoperitoneal shunt placement: illustrative case.Journal of neurosurgery. Case lessons · 2021Article
- Boundary conditions investigation to improve computer simulation of cerebrospinal fluid dynamics in hydrocephalus patients.Communications biology · 2021Article
- Management of ventriculo-gallbladder shunt in the presence of gallstones.BMJ case reports · 2020Article
- Finite element analysis of occlusal splint therapy in patients with bruxism.BMC oral health · 2019Article
- Minimizing thermal damage to vascular nerves while drilling of calcified plaque.BMC research notes · 2019Article
- The effect of spatial distances between holes and time delays between bone drillings based on examination of heat accumulation and risk of bone thermal necrosis.Biomedical engineering online · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionHydrocephalus is one of the most common diseases in children, and its treatment requires brain operation. However, the pathophysiology of the disease is very complicated and still unknown.
methodsEndoscopic Third Ventriculostomy (ETV) and Ventriculoperitoneal Shunt (VPS) implantation are among the common treatments of hydrocephalus. In this study, Cerebrospinal Fluid (CSF) hydrodynamic parameters and efficiency of the treatment methods were compared with numerical simulation and clinical follow-up of the treated patients.
resultsStudies have shown that in patients under 19 years of age suffering from hydrocephalus related to a Posterior Fossa Brain Tumor (PFBT), the cumulative failure rate was 21% and 29% in ETV and VPS operation, respectively. At first, the ETV survival curve shows a sharp decrease and after two months it gets fixed while VPS curve makes a gradual decrease and reaches to a level lower than ETV curve after 5.7 months. Post-operative complications in ETV and VPS methods are 17% and 31%, respectively. In infants younger than 12 months with hydrocephalus due to congenital Aqueduct Stenosis (AS), and also in the elderly patients suffering from Normal Pressure Hydrocephalus (NPH), ETV is a better treatment option. Computer simulations show that the maximum CSF pressure is the most reliable hydrodynamic index for the evaluation of the treatment efficacy in these patients. After treatment by ETV and shunt methods, CSF pressure decreases about 9 and 5.3 times, respectively and 2.5 years after shunt implantation, this number returns to normal range.
conclusionIn infants with hydrocephalus, initial treatment by ETV was more reasonable than implanting the shunt. In adult with hydrocephalus, the initial failure in ETV occurred sooner compared to shunt therapy; however, ETV was more efficient.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.