Evidence map›Paper›PMID 31462973›Full record

ReviewComputational and structural biotechnology journal2019

Drug Inducible CRISPR/Cas Systems.

Jingfang Zhang, Li Chen, Ju Zhang, Yu Wang

Open access · goldAbstract readReview
In one paragraph

Review in Computational and structural biotechnology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 64 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Cell Immortality:Life (Basel, Switzerland) · 2024
    Review
  14. Article
  15. Online Databases of Genome Editing in Cardiovascular and Metabolic Diseases.Advances in experimental medicine and biology · 2023
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jingfang ZhangSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing 100029, China.
Li ChenState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Ju ZhangState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Yu WangState Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Beijing University of Chinese Medicine · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clustered, regularly interspaced, short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) systems have been employed as a powerful versatile technology for programmable gene editing, transcriptional modulation, epigenetic modulation, and genome labeling,

Indexed as

4-OHT, 4-HydroxytamoxifenABA, abscisic acidADs, activation domainsarC9, allosterically regulated Cas9Cas, CRISPR-associated proteinCIP, chemically induced proximityCRISPR, clustered, regularly interspaced, short palindromic repeatsCrRNA, CRISPR RNAdCas9, dead Cas9dCpf1, dead Cpf1DD, destabilizing domainDHFR, dihydrofolate reductasedLbCpf1, Lachnospiraceae bacterium dCpf1dox, doxycyclineER, Estrogen ReceptorFKBP, FK506-binding proteinFRB, FKBP-rapamycin-binding domainGA, gibberellinHIT, Hybrid drug Inducible CRISPR/Cas9 TechnologiesHsp90, heat shock protein 90iPSCs, induced pluripotent stem cellsLBD, ligand binding domainLSL, loxP-stop-loxPMST, multiplex single transcriptNES, nuclear export sequenceNLS, nuclear localization sequencePtet, tetO-containing promoterrtTA, reverse-tTASa, Staphylococcus areussgRNA, single guide RNASp, Streptococcus pyogenesTetO, tet operatorTetR, Tet repressor proteinTMP, trimethoprimTRE3G, Tet-On 3G proteinTRE, tetracycline response elementVPR, VP64-P65-Rta

Identifiers

PMID31462973
PMCPMC6709367
OpenAlexW2966325079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.