Evidence map›Paper›PMID 31462926›Full record

ArticleBiotechnology for biofuels2019

Drop-in biofuel production using fatty acid photodecarboxylase from

Stefan Bruder, Eva Johanna Moldenhauer, Robert Denis Lemke, Rodrigo Ledesma-Amaro, Johannes Kabisch

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 88 citations in OpenAlex.

  1. Toward Sustainability: Intensification of Light-Driven Whole Cell Biocatalysis.Chembiochem : a European journal of chemical biology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Cavity-Based Discovery of New Fatty Acid Photodecarboxylases.Chembiochem : a European journal of chemical biology · 2024
    Article
  9. Article
  10. Automation-aided construction and characterization ofFrontiers in bioengineering and biotechnology · 2024
    Article
  11. Review
  12. Article
  13. Ultrafast Dynamics and Catalytic Mechanism of Fatty Acid Photodecarboxylase.Angewandte Chemie (International ed. in English) · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Stabilisation of the Fatty Acid Decarboxylase from Chlorella variabilis by Caprylic Acid.Chembiochem : a European journal of chemical biology · 2021
    Article
  18. Journal of fungi (Basel, Switzerland) · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Stefan Bruder1Computer-Aided Synthetic Biology, Technische Universität Darmstadt, Schnittspahnstr. 12, 64287 Darmstadt, Germany.
Eva Johanna Moldenhauer1Computer-Aided Synthetic Biology, Technische Universität Darmstadt, Schnittspahnstr. 12, 64287 Darmstadt, Germany.
Robert Denis Lemke1Computer-Aided Synthetic Biology, Technische Universität Darmstadt, Schnittspahnstr. 12, 64287 Darmstadt, Germany.
Rodrigo Ledesma-Amaro2Department of Bioengineering and Imperial College Centre for Synthetic Biology, Imperial College London, London, UK.
Johannes Kabisch1Computer-Aided Synthetic Biology, Technische Universität Darmstadt, Schnittspahnstr. 12, 64287 Darmstadt, Germany.ORCID 0000-0002-9679-3038
Technische Universität Darmstadt · DEImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOleaginous yeasts are potent hosts for the renewable production of lipids and harbor great potential for derived products, such as biofuels. Several promising processes have been described that produce hydrocarbon drop-in biofuels based on fatty acid decarboxylation and fatty aldehyde decarbonylation. Unfortunately, besides fatty aldehyde toxicity and high reactivity, the most investigated enzyme, aldehyde-deformylating oxygenase, shows unfavorable catalytic properties which hindered high yields in previous metabolic engineering approaches.

resultsTo demonstrate an alternative alkane production pathway for oleaginous yeasts, we describe the production of diesel-like, odd-chain alkanes and alkenes, by heterologously expressing a recently discovered light-driven oxidase from

conclusionsOleaginous yeasts such as

Indexed as

AlkaneAlkeneClean fuelsDrop-in biofuelsFatty acid photodecarboxylaseHydrocarbonsMicrobial biodieselOleaginous yeastYarrowia lipolytica

Identifiers

PMID31462926
PMCPMC6708191
OpenAlexW2969474682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.