ArticleScientific reports2019
Molecular evidence for origin, diversification and ancient gene duplication of plant subtilases (SBTs).
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 26 citations in OpenAlex.
- Evolutionary shifts in plant adaptation mediated by phytohormones.Plant communications · 2026Review
- Comprehensive Analyses of Serine Protease-like Protease (SBT) in Regulating Yield Characters in Rapeseed (Plants (Basel, Switzerland) · 2026Article
- Genome-Wide Identification, Functional Characterization, and Stress-Responsive Expression Profiling of Subtilase (International journal of molecular sciences · 2024Article
- Overlooked and misunderstood: can glutathione conjugates be clues to understanding plant glutathione transferases?Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Review
- The lowdown on breakdown: Open questions in plant proteolysis.The Plant cell · 2024Review
- Genomes of multicellular algal sisters to land plants illuminate signaling network evolution.Nature genetics · 2024Article
- Genome-Wide Investigation and Co-Expression Network Analysis of SBT Family Gene inInternational journal of molecular sciences · 2023Article
- Chromosome-level genomes of multicellular algal sisters to land plants illuminate signaling network evolution.bioRxiv : the preprint server for biology · 2023Article
- Genome-Wide Identification and Analysis of the Maize Serine Peptidase S8 Family Genes in Response to Drought at Seedling Stage.Plants (Basel, Switzerland) · 2023Article
- COVID-19 Pathology Sheds Further Light on Balance between Neutrophil Proteases and Their Inhibitors.Biomolecules · 2022Review
- Bacterial-type ferroxidase tunes iron-dependent phosphate sensing during Arabidopsis root development.Current biology : CB · 2022Article
- Recent insights on gene expression studies onPhysiology and molecular biology of plants : an international journal of functional plant biology · 2022Review
- Phylogenetic survey of the subtilase family and a data-mining-based search for new subtilisins fromFrontiers in microbiology · 2022Article
- A Transcriptomic Approach Provides Insights on the Mycorrhizal Symbiosis of the Mediterranean OrchidPlants (Basel, Switzerland) · 2021Article
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Authors and funding
9 authors at 3 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Plant subtilases (SBTs) are a widely distributed family of serine proteases which participates in plant developmental processes and immune responses. Although SBTs are divided into seven subgroups in plants, their origin and evolution, particularly in green algae remain elusive. Here, we present a comprehensive large-scale evolutionary analysis of all subtilases. The plant subtilases SBT1-5 were found to be monophyletic, nested within a larger radiation of bacteria suggesting that they originated from bacteria by a single horizontal gene transfer (HGT) event. A group of bacterial subtilases comprising representatives from four phyla was identified as a sister group to SBT1-5. The phylogenetic analyses, based on evaluation of novel streptophyte algal genomes, suggested that the recipient of the HGT of bacterial subtilases was the common ancestor of Coleochaetophyceae, Zygnematophyceae and embryophytes. Following the HGT, the subtilase gene duplicated in the common ancestor and the two genes diversified into SBT2 and SBT1, 3-5 respectively. Comparative structural analysis of homology-modeled SBT2 proteins also showed their conservation from bacteria to embryophytes. Our study provides the first molecular evidence about the evolution of plant subtilases via HGT followed by a first gene duplication in the common ancestor of Coleochaetophyceae, Zygnematophyceae, and embryophytes, and subsequent expansion in embryophytes.
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