Evidence map›Paper›PMID 31462548›Full record

ArticleJournal of clinical microbiology2019

Pilot Evaluation of a Fully Automated Bioinformatics System for Analysis of Methicillin-Resistant Staphylococcus aureus Genomes and Detection of Outbreaks.

Nicholas M Brown, Beth Blane, Kathy E Raven, Narender Kumar, Danielle Leek, Eugene Bragin, Paul A Rhodes, David A Enoch, Rachel Thaxter, Julian Parkhill and 1 more

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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  8. Digital microbiology.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Nicholas M Brown *Clinical Microbiology and Public Health Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Beth Blane *Department of Medicine, University of Cambridge, Cambridge, United Kingdom eb544@medschl.cam.ac.uk.
Kathy E RavenDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Narender KumarDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Danielle LeekDepartment of Medicine, University of Cambridge, Cambridge, United Kingdom.
Eugene BraginNext Gen Diagnostics, Hinxton, United Kingdom.
Paul A RhodesNext Gen Diagnostics, Mountain View, California, USA.
David A EnochClinical Microbiology and Public Health Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Rachel ThaxterClinical Microbiology and Public Health Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
Julian ParkhillWellcome Sanger Institute, Hinxton, United Kingdom.ORCID 0000-0002-7069-5958
Sharon J PeacockClinical Microbiology and Public Health Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.
University of Cambridge · GBCambridge University Hospitals NHS Foundation Trust · GBWellcome Sanger Institute · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

Genomic surveillance that combines bacterial sequencing and epidemiological information will become the gold standard for outbreak detection, but its clinical translation is hampered by the lack of automated interpretation tools. We performed a prospective pilot study to evaluate the analysis of methicillin-resistant

Indexed as

Automation, LaboratoryComputational BiologyDisease OutbreaksGenome, BacterialAnti-Bacterial AgentsBacterial Typing TechniquesEnglandHumansMethicillinMethicillin-Resistant Staphylococcus aureusMultilocus Sequence TypingPilot ProjectsProspective StudiesSequence Analysis, DNAStaphylococcal InfectionsWhole Genome SequencingAnti-Bacterial AgentsMethicillinbioinformaticsmicrobiologyStaphylococcus aureuswhole-genome sequencing

Identifiers

PMID31462548
PMCPMC6813015
OpenAlexW2970395337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.