Evidence map›Paper›PMID 31462532›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Satish R Ghimire, Michael R Deans

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The RNA-binding protein TRIM71 is essential for hearing in humans and mice and times auditory sensory organ development.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Frizzled receptors: gatekeepers of Wnt signaling in development and disease.Frontiers in cell and developmental biology · 2025
    Review
  8. Article
  9. Early Steps towards Hearing: Placodes and Sensory Development.International journal of molecular sciences · 2023
    Review
  10. Article
  11. The role of Evi/Wntless in exporting Wnt proteins.Development (Cambridge, England) · 2023
    Review
  12. Wiring the senses: Factors that regulate peripheral axon pathfinding in sensory systems.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Review
  20. Frontiers in neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Satish R GhimireDepartment of Neurobiology & Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84132, and.
Michael R DeansDepartment of Neurobiology & Anatomy, University of Utah School of Medicine, Salt Lake City, Utah 84132, and michael.deans@utah.edu.
University of Utah · US

Funding

Planar Polarity Mechanisms in Mammalian Inner Ear DevelopmentR01DC013066 · NIDCD · UNIVERSITY OF UTAH · PI MICHAEL R DEANS · 2013 to 2026
$4.7M
Genetic Dissection of Vangl2-Dependent Axon Guidance in the Developing CochleaR21DC015635 · NIDCD · UNIVERSITY OF UTAH · PI DEANS, MICHAEL R · 2017 to 2018
$418k
NIDCD NIH HHS R01 DC013066NIDCD NIH HHS R21 DC015635
6 · The paper itself

Abstract

Type II spiral ganglion neurons provide afferent innervation to outer hair cells of the cochlea and are proposed to have nociceptive functions important for auditory function and homeostasis. These neurons are anatomically distinct from other classes of spiral ganglion neurons because they extend a peripheral axon beyond the inner hair cells that subsequently makes a distinct 90 degree turn toward the cochlear base. As a result, patterns of outer hair cell innervation are coordinated with the tonotopic organization of the cochlea. Previously, it was shown that peripheral axon turning is directed by a nonautonomous function of the core planar cell polarity (PCP) protein VANGL2. We demonstrate using mice of either sex that

Indexed as

AcyltransferasesAnimalsAxonsCell PolarityCochleaFemaleFrizzled ReceptorsHair Cells, Auditory, InnerHair Cells, Auditory, OuterMaleMembrane ProteinsMiceMutationNerve Tissue ProteinsNeuronsOrgan of CortiAcyltransferasesCelsr1 protein, mouseFrizzled ReceptorsFzd3 protein, mouseFzd6 protein, mouseLtap protein, mouseMembrane ProteinsNerve Tissue ProteinsPorcn protein, mouseReceptors, G-Protein-Coupledauditoryaxoncochleafrizzledplanar cell polarityspiral ganglia

Identifiers

PMID31462532
PMCPMC6786817
OpenAlexW2970536035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.