Evidence map›Paper›PMID 31462413›Full record

ArticlemSphere2019

Bacteria Detected in both Urine and Open Wounds in Nursing Home Residents: a Pilot Study.

Josie Libertucci, Christine M Bassis, Marco Cassone, Kristen Gibson, Bonnie Lansing, Lona Mody, Vincent B Young, Jennifer Meddings

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Josie LibertucciDepartment of Internal Medicine, Infectious Diseases Division, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0002-0052-9882
Christine M BassisDepartment of Internal Medicine, Infectious Diseases Division, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Marco CassoneDepartment of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Kristen GibsonDepartment of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Bonnie LansingDepartment of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Lona ModyDepartment of Internal Medicine, Division of Geriatric and Palliative Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Vincent B YoungDepartment of Internal Medicine, Infectious Diseases Division, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0003-3687-2364
Jennifer MeddingsCenter for Clinical Management Research, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA meddings@med.umich.edu.
University of Michigan · US

Funding

Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
Systems biology of Clostridium difficile infectionU01AI124255 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLOSS, PATRICK DAVID, YOUNG, VINCENT B · 2016 to 2020
$9.8M
Targeted Infection Prevention (TIP) Program in Nursing HomesR01AG032298 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MODY, LONA · 2009 to 2013
$1.7M
Diversity and stability relationships in the murine microbiomeR01GM099514 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLOSS, PATRICK DAVID · 2012 to 2015
$1.4M
Preventing Infections and Antimicrobial Resistance in the Aging Population: Translational Research and Training ProgramK24AG050685 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lona Mody · 2015 to 2026
$1.4M
Targeting Hospital-Acquired Complications: Impact on the Care of Complex PatientsK08HS019767 · AHRQ · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MEDDINGS, JENNIFER ANN · 2010 to 2014
$758k
Development of reproducible informatics skills among microbiome researchersR25GM116149 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SCHLOSS, PATRICK DAVID · 2015 to 2016
$148k
AHRQ HHS K08 HS019767NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR002240NIAID NIH HHS U01 AI124255NIA NIH HHS K24 AG050685NIA NIH HHS P30 AG024824NIA NIH HHS R01 AG032298NIGMS NIH HHS R01 GM099514NIGMS NIH HHS R25 GM116149
6 · The paper itself

Abstract

Nursing home residents are at a greater risk of developing pressure injuries that develop into an open wound, which can become colonized with bacteria. Understanding the factors that influence microbial colonization of open wounds can lead to the prevention of infections. The relationship between bacteria found in urine and those in open wounds is currently unknown. To determine if bacterial species colonizing open wounds are also found in the urine, we conducted a pilot study with nursing home residents, comparing bacterial species present in the urine with those present in wounds between the umbilicus and mid-thigh. To identify microbial species that were present in both urine and open wound at one time point in one patient, standard clinical bacteriologic culture techniques followed by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) were used, as well as 16S rRNA-encoding gene amplicon sequencing. We found some bacterial species detected in urine were also detected in open wounds in one individual at one time point, using both culture-dependent and -independent techniques. Bacterial species that were more often detected, using culture-dependent and -independent methods, at both sites included

Indexed as

MicrobiotaAgedBacteriaBacterial InfectionsBacteriological TechniquesHumansMaleNursing HomesPilot ProjectsQuality of LifeRNA, Ribosomal, 16SStem CellsWounds and InjuriesRNA, Ribosomal, 16Sbacteriologyclinical microbiologynursing home residentsurine microbiotawound microbiota

Identifiers

PMID31462413
PMCPMC6714893
OpenAlexW2970840983

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.