Evidence map›Paper›PMID 31462398›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2019

Obesity at Diagnosis and Prostate Cancer Prognosis and Recurrence Risk Following Primary Treatment by Radical Prostatectomy.

Crystal S Langlais, Janet E Cowan, John Neuhaus, Stacey A Kenfield, Erin L Van Blarigan, Jeanette M Broering, Matthew R Cooperberg, Peter Carroll, June M Chan

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Crystal S LanglaisDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California. crystal.langlais@ucsf.edu.ORCID 0000-0001-5654-5542
Janet E CowanDepartment of Urology, University of California, San Francisco, San Francisco, California.
John NeuhausDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Stacey A KenfieldDepartment of Urology, University of California, San Francisco, San Francisco, California.
Erin L Van BlariganDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.ORCID 0000-0001-5079-3385
Jeanette M BroeringDepartment of Urology, University of California, San Francisco, San Francisco, California.ORCID 0000-0002-7580-8931
Matthew R CooperbergDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Peter CarrollDepartment of Urology, University of California, San Francisco, San Francisco, California.
June M ChanDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
University of California, San Francisco · US

Funding

Translational Epidemiology - Training for Research on Aging and Chronic diseaseT32AG049663 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Elizabeth Rose Mayeda, Mark J Pletcher · 2016 to 2026
$5.8M
Diet After Colorectal Cancer : Observational Studies to Behavioral InterventionsK07CA197077 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VAN BLARIGAN, ERIN LYNN · 2016 to 2020
$885k
NCI NIH HHS K07 CA197077NIA NIH HHS T32 AG049663
6 · The paper itself

Abstract

backgroundThe association of obesity at diagnosis with prostate cancer progression is uncertain. This study aimed to examine the relationship between body mass index (BMI; 18.5-<25, 25-<30, 30-<35, ≥35 kg/m

methodsWe examined men enrolled in CaPSURE who underwent radical prostatectomy between 1995 and 2017. Multiple imputation methods were used to handle missing data and reported along with complete case findings.

resultsParticipants (

conclusionsOur findings suggest that residual confounding may partially explain the conflicting evidence regarding obesity's influence on prostate cancer progression. Assessing T-stage via digital rectal exam may be complicated in larger men, potentially affecting clinical treatment decisions. A strong association with all-cause mortality demonstrates healthier BMI at diagnosis may still improve overall survival. IMPACT: Patients with greater BMI are prone to more advanced disease at diagnosis and may be more likely to have their tumor stage underestimated at diagnosis.

Indexed as

Disease ProgressionHumansMaleMiddle AgedObesityProstatectomyProstatic NeoplasmsRecurrenceRisk Factors

Identifiers

PMID31462398
PMCPMC6825577
OpenAlexW2970120857

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.