Evidence map›Paper›PMID 31462267›Full record

ArticleRadiation oncology (London, England)2019

Impact of patient and treatment characteristics on heart and lung dose in adjuvant radiotherapy for left-sided breast cancer.

Tobias Finazzi, Van-Trinh Nguyen, Frank Zimmermann, Alexandros Papachristofilou

Open access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. "After radiation sessions, I sometimes feel weak and dizzy'': Experiences of Ghanaian women with breast cancer post radiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. "The disease and its treatment make you less of a woman": self-reported experiences of women with breast cancer receiving care in Kumasi, Ghana.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Correlation between gastric volume and organs at risk dose in adjuvant radiotherapy for left breast cancer.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2021
    Article
  11. Article
  12. Recent advances in radiotherapy of breast cancer.Radiation oncology (London, England) · 2020
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Tobias FinazziClinic of Radiotherapy and Radiation Oncology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland. tobias.finazzi@usb.ch.ORCID http://orcid.org/0000-0002-4118-4171
Van-Trinh NguyenClinic of Radiotherapy and Radiation Oncology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Frank ZimmermannClinic of Radiotherapy and Radiation Oncology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.
Alexandros PapachristofilouClinic of Radiotherapy and Radiation Oncology, University Hospital Basel, Petersgraben 4, 4031, Basel, Switzerland.ORCID http://orcid.org/0000-0001-5619-747X
University Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe heart and lungs are routinely exposed to incidental irradiation during adjuvant radiotherapy (RT) of breast cancer. We analyzed the impact of patient and treatment characteristics on heart and lung dose in left-sided breast RT.

methodsWe analyzed 332 female patients treated with left-sided breast RT between 2013 and 2018. Mean heart dose (MHD), left mean lung dose (MLD) and heart / lung V

resultsLN-RT was performed in 111 patients with increased MHD (median 4.6 vs. 3.3 Gy; p < .01), left MLD (14.8 vs. 7.7 Gy; p < .01) and left lung V

conclusionsIn adjuvant RT for left-sided breast cancer, LN-RT is associated with a marked increase in heart and lung doses, particularly with internal mammary LN-RT. Potential advantages of IMRT/VMAT for breast or chest wall RT need to be weighed against a moderately increased lung dose.

Indexed as

AdultAgedAged, 80 and overFemaleHeartHumansLungMiddle AgedOrgans at RiskPrognosisRadiotherapy, AdjuvantRadiotherapy, ConformalRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRetrospective StudiesUnilateral Breast NeoplasmsAdjuvant radiotherapyBreast cancerHeart doseIntensity-modulated radiotherapyLung doseLymph nodesOrgans at risk

Identifiers

PMID31462267
PMCPMC6714299
OpenAlexW2970731278

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.