Evidence map›Paper›PMID 31462235›Full record

ArticleRespiratory research2019

Validation of the IPF-specific version of St. George's Respiratory Questionnaire.

Thomas Skovhus Prior, Nils Hoyer, Saher Burhan Shaker, Jesper Rømhild Davidsen, Janelle Yorke, Ole Hilberg, Elisabeth Bendstrup

Registry-linked trialAbstract readMulticenter StudyValidation Study
In one paragraph

Article in Respiratory research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02818712 (Health-related Quality of Life and Comorbidities in Danish Patients With Idiopathic Pulmonary Fibrosis - a Nationwide Follow-up), which is not on this map. Cited by 35 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02818712 completednot on this map

Health-related Quality of Life and Comorbidities in Danish Patients With Idiopathic Pulmonary Fibrosis - a Nationwide Follow-up

TypeobservationalSponsorAarhus University HospitalRan2016 to 2021Enrolled150ConditionsIdiopathic Pulmonary Fibrosis
3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Health-related quality of life of patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2020
    Pooled it
  5. Tele-Rehabilitation Program in Idiopathic Pulmonary Fibrosis-A Single-Center Randomized Trial.International journal of environmental research and public health · 2021
    Trial
  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Article
  11. Article
  12. Assessment of quality of life in IPF Patients: a multicenter observational study.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2024
    Article
  13. Article
  14. Validation of a Novel Clinical Dyspnea Scale - A Retrospective Pilot Study.The American journal of hospice & palliative care · 2024
    Article
  15. Review
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Effect of a Telerehabilitation program in sarcoidosis.Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas Skovhus PriorDepartment of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark. thbjer@rm.dk.ORCID http://orcid.org/0000-0002-0668-8454
Nils HoyerDepartment of Respiratory Medicine, Herlev-Gentofte University Hospital, Copenhagen, Denmark.
Saher Burhan ShakerDepartment of Respiratory Medicine, Herlev-Gentofte University Hospital, Copenhagen, Denmark.
Jesper Rømhild DavidsenDepartment of Respiratory Medicine, Odense University Hospital, Odense, Denmark.
Janelle YorkeUniversity of Manchester and The Christie NHS Foundation Trust, Manchester, UK.
Ole HilbergDepartment of Respiratory Medicine, Vejle Hospital, Vejle, Denmark.
Elisabeth BendstrupDepartment of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark.

Funding

Aarhus University -Boehringer Ingelheim Denmark -The Danish Lung Association's Fund -The Ellen and Knud Dalhoff Larsen's Fund -The Health Research Fund of the Central Denmark Region -TrygFonden 118860
6 · The paper itself

Abstract

backgroundPatients with idiopathic pulmonary fibrosis (IPF) have impaired health-related quality of life (HRQL). To measure HRQL, an IPF-specific version of the St. George's Respiratory Questionnaire (SGRQ-I) was developed, but not sufficiently validated. This study aimed to assess the validity (i.a. known-groups validity and concurrent validity) and test-retest reliability of SGRQ-I in IPF patients with different disease durations.

methodsPatients with IPF were consecutively recruited and completed SGRQ, SGRQ-I, King's Brief Interstitial Lung Disease questionnaire (K-BILD), University of California, San Diego Shortness of Breath Questionnaire (SOBQ) and Short Form-36 (SF-36) along with pulmonary function tests and a 6-min walk test (6MWT) at baseline. After two weeks, SGRQ-I and Global Rating of Change Scales (GRCS) were completed.

resultsAt baseline and after two weeks, 150 and 134 patients completed the questionnaires, respectively. The internal consistency of SGRQ-I was high (Cronbach's α = 0.92). Good concurrent validity was demonstrated by high intraclass correlation coefficients (ICC = 0.97), Bland-Altman plots and moderate to strong correlations to K-BILD, SOBQ and SF-36 (r = - 0.46 to 0.80). High ICC (0.92) and a Bland-Altman plot indicated good test-retest reliability. SGRQ-I was good at discriminating between patients with different stages of disease (Δscore > 18.1, effect sizes > 0.10). Validity was similar across groups of different disease duration.

conclusionsSGRQ-I proved to be valid at distinguishing between different disease severities, valid compared to other HRQL instruments, applicable across different disease durations and reliable upon repetition. SGRQ-I is a valid option for measuring HRQL in patients with IPF.

trial registrationThe study was registered at clinicaltrials.org ( NCT02818712 ) on 15 June 2016.

Indexed as

Quality of LifeTranslatingAgedAged, 80 and overCohort StudiesDenmarkFemaleHumansIdiopathic Pulmonary FibrosisMaleSurveys and QuestionnairesHealth-related quality of lifeIdiopathic pulmonary fibrosisInterstitial lung diseaseIPF-specific version of the St. George’s respiratory questionnaireK-BILDQuality of lifeSGRQSGRQ-I

Identifiers

PMID31462235
PMCPMC6714302

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.