ArticleBMC microbiology2019
Detection of Candidatus Neoehrlichia mikurensis in Norway up to the northern limit of Ixodes ricinus distribution using a novel real time PCR test targeting the groEL gene.
Article in BMC microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Microorganisms inInternational journal for parasitology. Parasites and wildlife · 2026Article
- Seasonal variation in prevalence of Borrelia burgdorferi sensu lato and Neoehrlichia mikurensis in Ixodes ricinus nymphs in southern Norway.Acta veterinaria Scandinavica · 2026Article
- Habitat-Specific Patterns of Tick-Borne Pathogens in Urban and Suburban Landscapes.Pathogens (Basel, Switzerland) · 2026Article
- Fever of unknown origin and splenomegaly in an immunosuppressed Swiss patient: case report of a Neoehrlichia mikurensis infection in a changing climate and review of the literature.Access microbiology · 2026Article
- Prevalence and clinical characteristics of Norwegians who report persistent health complaints attributed to tick bites or tick-borne diseases.BMC infectious diseases · 2025Article
- Molecular Surveillance ofPathogens (Basel, Switzerland) · 2025Article
- Seroprevalence of IgG Antibodies AgainstMicroorganisms · 2025Article
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- Wolbachia in Antarctic terrestrial invertebrates: Absent or undiscovered?Environmental microbiology reports · 2024Article
- Article
- Rickettsia species in Dermacentor reticulatus ticks feeding on human skin and clinical manifestations of tick-borne infections after tick bite.Scientific reports · 2023Article
- Neoehrlichia mikurensis in Danish immunocompromised patients: a retrospective cohort study.Annals of clinical microbiology and antimicrobials · 2023Article
- Herbivores in Arctic ecosystems: Effects of climate change and implications for carbon and nutrient cycling.Annals of the New York Academy of Sciences · 2022Review
- No molecular detection of tick-borne pathogens in the blood of patients with erythema migrans in Belgium.Parasites & vectors · 2022Article
- Unbiased Characterization of the Microbiome and Virome of Questing Ticks.Frontiers in microbiology · 2021Article
- Spatial patterns of pathogen prevalence in questing Ixodes ricinus nymphs in southern Scandinavia, 2016.Scientific reports · 2020Article
- Spatial data of Ixodes ricinus instar abundance and nymph pathogen prevalence, Scandinavia, 2016-2017.Scientific data · 2020Article
- Correction to: Detection of Candidatus Neoehrlichia mikurensis in Norway up to the northern limit of Ixodes ricinus distribution using a novel real time PCR test targeting the groEL gene.BMC microbiology · 2020Article
- Tick-borne pathogens in Ixodes ricinus ticks collected from migratory birds in southern Norway.PloS one · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCandidatus Neoehrlichia mikurensis is an emerging tick-borne pathogen. It is widely distributed in Ixodes ricinus ticks in Europe, but knowledge of its distribution in Norway, where I. ricinus reaches its northern limit, is limited. In this study we have developed a real time PCR test for Ca. N. mikurensis and used it to investigate the distribution of Ca. N. mikurensis in Norway.
resultsReal time PCR targeting the groEL gene was developed and shown to be highly sensitive. It was used to detect Ca. N. mikurensis in 1651 I. ricinus nymphs and adults collected from twelve locations in Norway, from the eastern Oslo Fjord in the south to near the Arctic Circle in the north. The overall prevalence was 6.5% and varied locally between 0 and 16%. Prevalence in adults and nymphs was similar, suggesting that ticks acquire Ca. N. mikurensis predominantly during their first blood meal. In addition, 123 larvae were investigated; Ca. N. mikurensis was not found in larvae, suggesting that transovarial transmission is rare or absent. Sequence analysis suggests that a single variant dominates in Norway.
conclusionsCa. N. mikurensis is widespread and common in ticks in Norway and reaches up to their northern limit near the Arctic Circle. Ticks appear to acquire Ca. N. mikurensis during their first blood meal. No evidence for transovarial transmission was found.
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