Evidence map›Paper›PMID 31462095›Full record

Observational studyAIDS care2020

Association between caregiver depression symptoms and child executive functioning. Results from an observational study carried out in four sub-Saharan countries.

Itziar Familiar, Miriam Chernoff, Horacio Ruisenor-Escudero, Barbara Laughton, Celeste Joyce, Lee Fairlie, Tichaona Vhembo, Portia Kamthunzi, Linda Barlow-Barlow, Bonnie Zimmer and 2 more

Abstract readObservational Study
In one paragraph

Observational study in AIDS care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. African Multi-Site 2-Year Neuropsychological Study of School-Age Children Perinatally Infected, Exposed, and Unexposed to Human Immunodeficiency Virus.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Itziar FamiliarDepartment of Psychiatry, Michigan State University, East Lansing, MI, USA.
Miriam ChernoffCenter for Biostatistics in AIDS Research, Harvard University, Boston, MA, USA.
Horacio Ruisenor-EscuderoDepartment of Psychiatry, Michigan State University, East Lansing, MI, USA.
Barbara LaughtonDepartment of Pediatrics and Child Health, Stellenboch University, Tygerberg, RSA.
Celeste JoycePerinatal HIV Research Unit (PHRU), Chris Hani Baragwanath Hospital, Johannesburg, RSA.
Lee FairlieWits Reproductive Health and HIV Institute, Shandukani Clinic, Johannesburg, RSA.
Tichaona VhemboHarare Family Care CRS, University of Zimbabwe, Harare, Zimbabwe.
Portia KamthunziUniversity of North Carolina-Lilongwe Clinical Research Institute, Lilongwe, Malawi.
Linda Barlow-BarlowMakerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.
Bonnie ZimmerFrontier Science Foundation, Amherst, MA, USA.
Katie McCarthyFHI 360, Durham, NC, USA.
Michael J BoivinDepartments of Psychiatry and Neurology, Michigan State University, East Lansing, MI, USA.

Funding

LOC-IMPAACT Leadership GroupPharmacokinetics and Safety of Remdesivir for Treatment of COVID-19 in Pregnant Women in the USUM1AI068632 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI Sharon A Nachman · 2011 to 2026
$278.1M
Statistical and Data Management Center-Pediatric,Adolescent, and Maternal CTGUM1AI068616 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Sean Scott Brummel, Marlene Ann Cooper · 2011 to 2026
$155.6M
University of North Carolina Global HIV Prevention and Treatment Clinical Trials Unit 2024 SupplementUM1AI069423 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, MINA CHRISTINE HOSSEINIPOUR · 2012 to 2026
$71.8M
LC - IMPAACT Leadership GroupUM1AI106716 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Grace M Aldrovandi · 2014 to 2026
$47.2M
Soweto Clinical Trials UnitUM1AI069453 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI Glenda E Gray, Lerato Mohapi · 2012 to 2026
$40.9M
Wits HIV Research Group CLINICAL TRIAL UNIT (CTU) reapplicationUM1AI069463 · NIAID · WITS HEALTH CONSORTIUM (PTY), LTD · PI REES, HELEN, SANNE, IAN MATTHIAS · 2012 to 2025
$31.8M
Stellenbosch University Clinical Trial Unit, Cape Town, South AfricaUM1AI069521 · NIAID · STELLENBOSCH UNIVERSITY · PI Shaun Barnabas, Anneke Catharina Hesseling · 2012 to 2026
$21.5M
Stellenbosch University Clinical Trial Unit, Cape Town, South AfricaU01AI069521 · NIAID · STELLENBOSCH UNIVERSITY · PI COTTON, MARK FREDRIC · 2007 to 2011
$8.4M
Developing appropriate risk reduction interventions for pre-teensR21MH083308 · NIMH · WITS HEALTH CONSORTIUM (PTY), LTD · PI GRAY, GLENDA E, SIKKEMA, KATHLEEN J · 2008 to 2009
$331k
NIAID NIH HHS UM1 AI068616NIAID NIH HHS UM1 AI068632NIAID NIH HHS UM1 AI069423NIAID NIH HHS UM1 AI069453NIAID NIH HHS UM1 AI069463NIAID NIH HHS UM1 AI069521NIAID NIH HHS UM1 AI106716NICHD NIH HHS HHSN275201800001CNICHD NIH HHS HHSN275201800001INIMH NIH HHS R21 MH083308
6 · The paper itself

Abstract

Depressive symptoms among HIV-positive (HIV+) women may negatively impact their health and possibly that of their young children through risk of compromised caregiving. We evaluated how depression symptoms in predominantly (97%) female caregivers relate to neurodevelopmental outcomes in their HIV affected children. Data come from the IMPAACT P1104s Study, an observational cohort across six sites in four countries: Zimbabwe, South Africa, Uganda and Malawi. Participants (

Indexed as

AdultAnti-Retroviral AgentsCaregiversChildChild, PreschoolCost of IllnessDepressionExecutive FunctionFemaleHIV InfectionsHumansMalawiMaleMiddle AgedNeurocognitive DisordersSouth AfricaAnti-Retroviral Agentschild neuropsychologyExecutive functioningHIV/AIDSsub-Saharan Africa

Identifiers

PMID31462095
PMCPMC7047586

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.