ArticleAnimals : an open access journal from MDPI2019
Anti-Inflammatory State in Arabian Horses Introduced to the Endurance Training.
Article in Animals : an open access journal from MDPI, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Effects of Exercise Intensity and Duration on Acute-Phase Proteins in Thoroughbred Racehorses.Animals : an open access journal from MDPI · 2026Article
- How Inflamed Is the Horse in Training? Insights into Exercise-Induced Acute Phase Response in Endurance Horses.International journal of molecular sciences · 2026Review
- Evaluation of Concentration Changes in Plasma Amino Acids and Their Metabolites in Eventing Horses During Cross-Country Competitions as Potential Performance Predictors.Animals : an open access journal from MDPI · 2025Article
- Iron Status in Sport Horses: Is It Important for Equine Athletes?International journal of molecular sciences · 2025Review
- Astaxanthin Supplementation Does Not Alter Training-Related Changes in Inflammatory Cytokine Profile in Arabian Racing Horses.Antioxidants (Basel, Switzerland) · 2024Article
- Immunology of Physical Exercise: IsInternational journal of molecular sciences · 2024Review
- Impact of Chlorogenic Acid on Peripheral Blood Mononuclear Cell Proliferation, Oxidative Stress, and Inflammatory Responses in Racehorses during Exercise.Antioxidants (Basel, Switzerland) · 2023Article
- Article
- Pre-Ride Biomarkers and Endurance Horse Welfare: Analyzing the Impact of the Elimination of Superoxide Dismutase, δ-Aminolevulinic-Dehydratase, Thiobarbituric Acid Reactive Substances, Iron, and Serum Amyloid A Levels in Elite 160 km Endurance Rides.Animals : an open access journal from MDPI · 2023Article
- Changes in novel anti-infalmmatory cytokine concetration in the bood of endurance and race horses at different levels of training.Computational and structural biotechnology journal · 2023Article
- Horse Racing as a Model to Study the Relationship between Air Pollutants and Physical Performance.Animals : an open access journal from MDPI · 2022Article
- The Influence of Intravaginal Gestagens Treatment on the Morphological Features and Endometrial Steroid Hormone Receptors Content during Anestrus Type II in Dairy Cattle.International journal of molecular sciences · 2022Article
- Article
- The Physical Activity-Dependent Hematological and Biochemical Changes in School Horses in Comparison to Blood Profiles in Endurance and Race Horses.Animals : an open access journal from MDPI · 2021Article
- Peripheral Modulators of the Central Fatigue Development and Their Relationship with Athletic Performance in Jumper Horses.Animals : an open access journal from MDPI · 2021Article
- Training Young Horses: The Science behind the Benefits.Animals : an open access journal from MDPI · 2021Review
- The Effect of Physical Training on Peripheral Blood Mononuclear Cell Ex Vivo Proliferation, Differentiation, Activity, and Reactive Oxygen Species Production in Racehorses.Antioxidants (Basel, Switzerland) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Development of an anti-inflammatory state during physical training has been postulated in both human and equine athletes, but it is not completely understood. The aim of this study was to investigate whether endurance training changes pro- and anti-inflammatory cytokine profiles within a 20-week training season in young inexperienced endurance horses. Nine Arabian horses were examined in this prospective 20-week follow-up study. Blood samples were analysed 5 times monthly, at rest and after training sessions. Routine haematological examinations were performed. Cytokine patterns including IL-1β, IL-6, TNF-α, IL-10 mRNA expression using Real Time-PCR, and serum concentrations of IL-1β, IL-2, IL-4, IL-6, IL-17, INFγ, TNF-α, and IL-10 by ELISA test were determined. During endurance training, the most significant decrease in post-exercise cytokine type 1 levels (TNFα and IL-β) occurred within 20 weeks, beginning from the 3rd month of training. IL-6 serum level decreased after the 4th month. The results suggest that endurance training can induce advanced overall anti-inflammatory response as an adaptation to increasing workload.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.