Evidence map›Paper›PMID 31461990›Full record

ReviewAntibiotics (Basel, Switzerland)2019

Phage Therapy with a Focus on the Human Microbiota.

Sharita Divya Ganeshan, Zeinab Hosseinidoust

Abstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers.

0numbers the graph read from it
0cells of the map it votes in
84citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

84 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Newly isolatedFrontiers in microbiology · 2026
    Article
  12. Review
  13. Bacteriophages targetingFrontiers in microbiology · 2026
    Review
  14. Review
  15. Microbial keratitis in the age of resistance: unlocking the therapeutic potential of phage therapy.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Review
  16. Review
  17. Review
  18. Review
  19. Risk Profile of Bacteriophages in the Food Chain.Foods (Basel, Switzerland) · 2025
    Review
  20. Article

24 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sharita Divya GaneshanSchool of Biomedical Engineering, McMaster University, Hamilton, ON L8S 4K1, Canada.
Zeinab HosseinidoustSchool of Biomedical Engineering, McMaster University, Hamilton, ON L8S 4K1, Canada. doust@mcmaster.ca.ORCID 0000-0001-9261-7611

Funding

Farncombe Family Digestive Health Research Institute NANatural Sciences and Engineering Research Council of Canada NA
6 · The paper itself

Abstract

Bacteriophages are viruses that infect bacteria. After their discovery in the early 1900s, bacteriophages were a primary cure against infectious disease for almost 25 years, before being completely overshadowed by antibiotics. With the rise of antibiotic resistance, bacteriophages are being explored again for their antibacterial activity. One of the critical apprehensions regarding bacteriophage therapy, however, is the possibility of genome evolution, development of phage resistance, and subsequent perturbations to our microbiota. Through this review, we set out to explore the principles supporting the use of bacteriophages as a therapeutic agent, discuss the human gut microbiome in relation to the utilization of phage therapy, and the co-evolutionary arms race between host bacteria and phage in the context of the human microbiota.

Indexed as

antibiotic resistanceevolutionmicrobiome therapyphage therapy

Identifiers

PMID31461990
PMCPMC6783874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.