Evidence map›Paper›PMID 31461953›Full record

ArticleViruses2019

Crystal Structure of African Swine Fever Virus A179L with the Autophagy Regulator Beclin.

Suresh Banjara, Gareth L Shimmon, Linda K Dixon, Christopher L Netherton, Mark G Hinds, Marc Kvansakul

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 46 citations in OpenAlex.

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  16. African Swine Fever Virus: A Review.Life (Basel, Switzerland) · 2022
    Review
  17. Article
  18. The Multi-Faceted Role of Autophagy During Animal Virus Infection.Frontiers in cellular and infection microbiology · 2022
    Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Suresh BanjaraDepartment of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia.
Gareth L ShimmonPirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.
Linda K DixonPirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.
Christopher L NethertonPirbright Institute, Ash Road, Pirbright, Surrey GU24 0NF, UK.
Mark G HindsBio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria 3050, Australia. hinds.mark.g@gmail.com.
Marc KvansakulDepartment of Biochemistry & Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria 3086, Australia. m.kvansakul@latrobe.edu.au.
The Pirbright Institute · GBLa Trobe University · AUUniversity of Melbourne · AU

Funding

Biotechnology and Biological Sciences Research Council BBS/E/I/0000Biotechnology and Biological Sciences Research Council BBS/E/I/00002120Biotechnology and Biological Sciences Research Council BBS/E/I/00007030Biotechnology and Biological Sciences Research Council BBS/E/I/00007031Biotechnology and Biological Sciences Research Council BBS/E/I/00007034Biotechnology and Biological Sciences Research Council BBS/E/I/00007035Biotechnology and Biological Sciences Research Council BBS/E/I/00007036Biotechnology and Biological Sciences Research Council BBS/E/I/00007037Biotechnology and Biological Sciences Research Council BBS/E/I/00007038Biotechnology and Biological Sciences Research Council BBS/E/I/00007039
6 · The paper itself

Abstract

Subversion of programmed cell death-based host defence systems is a prominent feature of infections by large DNA viruses. African swine fever virus (ASFV) is a large DNA virus and sole member of the

Indexed as

AutophagyAfrican Swine Fever VirusAnimalsApoptosis Regulatory ProteinsBeclin-1Chlorocebus aethiopsCrystallography, X-RayHumansMutationPeptide FragmentsProtein BindingProto-Oncogene ProteinsProto-Oncogene Proteins c-bcl-2Structure-Activity RelationshipVero CellsViral ProteinsA179L protein, African Swine Fever VirusApoptosis Regulatory ProteinsBax protein (53-86)Beclin-1Peptide FragmentsProto-Oncogene ProteinsProto-Oncogene Proteins c-bcl-2Viral ProteinsASFVautophagyBcl-2BeclinX-ray crystallography

Identifiers

PMID31461953
PMCPMC6784060
OpenAlexW2966716049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.