Evidence map›Paper›PMID 31461851›Full record

ArticleCells2019

Regulation of I

Yong Li, Thomas Hof, Tanya A Baldwin, Lei Chen, Robert S Kass, Carmen W Dessauer

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Compartmentalized cAMP signalling and control of cardiac rhythm.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  4. Article
  5. In Vivo Cardiac-specific Expression of Adenylyl Cyclase 4 Gene Protects against Klotho Deficiency-induced Heart Failure.Translational research : the journal of laboratory and clinical medicine · 2022
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. AKAP Signaling Islands: Venues for Precision Pharmacology.Trends in pharmacological sciences · 2020
    Review
  12. Article
  13. Neurohormonal Regulation of IJournal of the American Heart Association · 2020
    Review
  14. Nanometric targeting of type 9 adenylyl cyclase in heart.Biochemical Society transactions · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yong LiDepartment of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030, USA.ORCID 0000-0001-7440-6933
Thomas HofDepartment of Pharmacology, Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
Tanya A BaldwinDepartment of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030, USA.ORCID 0000-0001-7142-639X
Lei ChenDepartment of Pharmacology, Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
Robert S KassDepartment of Pharmacology, Department of Medicine, College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA.
Carmen W DessauerDepartment of Integrative Biology and Pharmacology, McGovern Medical School, University of Texas Health Science Center, Houston, TX 77030, USA. carmen.w.dessauer@uth.tmc.edu.ORCID 0000-0003-1210-4280
Columbia University · USThe University of Texas Health Science Center at Houston · US

Funding

REGULATION OF ADENYLYL CYCLASE SIGNALING PATHWAYSR01GM060419 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI DESSAUER, CARMEN W. · 2000 to 2021
$6.9M
NIGMS NIH HHS R01 GM060419
6 · The paper itself

Abstract

The subunits KCNQ1 and KCNE1 generate the slowly activating, delayed rectifier potassium current, I

Indexed as

Adenylyl CyclasesAnimalsIsoproterenolKCNQ1 Potassium ChannelMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicMyocytes, CardiacPhosphorylationadenylate cyclase 9Adenylyl CyclasesIsoproterenolKCNQ1 Potassium ChannelKcnq1 protein, mouseAC9adenylyl cyclaseAKAPA-kinase anchoring proteincardiomyocytecyclic AMPKCNQ1potassium channelsprotein kinase AYotiao

Identifiers

PMID31461851
PMCPMC6770663
OpenAlexW2970772407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.