Evidence map›Paper›PMID 31461630›Full record

ArticleAmerican journal of respiratory and critical care medicine2020

Dynamics of IFN-β Responses during Respiratory Viral Infection. Insights for Therapeutic Strategies.

Alastair Watson, C Mirella Spalluto, Christopher McCrae, Doriana Cellura, Hannah Burke, Danen Cunoosamy, Anna Freeman, Alex Hicks, Michael Hühn, Kristoffer Ostridge and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in American journal of respiratory and critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 72 citations in OpenAlex.

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  3. INEXAS: A Phase 2 Randomized Trial of On-demand Inhaled Interferon Beta-1a in Severe Asthmatics.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Alastair WatsonClinical and Experimental Sciences, University of Southampton Faculty of Medicine, and.ORCID 0000-0002-6735-2567
C Mirella SpallutoClinical and Experimental Sciences, University of Southampton Faculty of Medicine, and.
Christopher McCraeBioscience, Research and Early Development-Respiratory, Inflammation and Autoimmunity, R&D BioPharmaceuticals, AstraZeneca, Gaithersburg, Maryland.
Doriana CelluraClinical and Experimental Sciences, University of Southampton Faculty of Medicine, and.
Hannah BurkeClinical and Experimental Sciences, University of Southampton Faculty of Medicine, and.
Danen CunoosamyTranslational Science and Experimental Medicine, and.
Anna FreemanClinical and Experimental Sciences, University of Southampton Faculty of Medicine, and.
Alex HicksClinical and Experimental Sciences, University of Southampton Faculty of Medicine, and.
Michael HühnTranslational Science and Experimental Medicine, and.
Kristoffer OstridgeClinical and Experimental Sciences, University of Southampton Faculty of Medicine, and.ORCID 0000-0001-8910-3900
Karl J StaplesClinical and Experimental Sciences, University of Southampton Faculty of Medicine, and.ORCID 0000-0003-3844-6457
Outi VaaralaBioscience, Research and Early Development-Respiratory, Inflammation and Autoimmunity, R&D BioPharmaceuticals, AstraZeneca, Gaithersburg, Maryland.
Tom WilkinsonClinical and Experimental Sciences, University of Southampton Faculty of Medicine, and.
Southampton General Hospital · GBBioscience Research · USUniversity of Southampton · GB

Funding

Medical Research Council MR/K002597/1Wellcome Trust 201244/Z/16/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAged, 80 and overAntiviral AgentsAsthmaFemaleHumansInterferon-betaMaleMiddle AgedPulmonary Disease, Chronic ObstructiveVirus DiseasesAntiviral AgentsInterferon-betachronic obstructive pulmonary diseaseexacerbationinnate immunityrespiratory viruses

Identifiers

PMID31461630
OpenAlexW2971183359

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.