ArticlePloS one2019
Melatonin acts synergistically with auxin to promote lateral root development through fine tuning auxin transport in Arabidopsis thaliana.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 94 citations in OpenAlex.
- Classical Phytohormones and Peptide Plant Hormones in Abiotic Stress Tolerance: Crosstalk, Physiological Integration, and Crop Improvement.Plants (Basel, Switzerland) · 2026Review
- Exogenous Melatonin Increases Root Yield and Its Medicinal Quality ofPlants (Basel, Switzerland) · 2025Article
- Melatonin microbe interactions in plant rhizosphere.iScience · 2025Review
- Molecular insights into melatonin-mediated stress tolerance in rice.Plant cell reports · 2025Review
- The potential of melatonin in the mitigation of adverse effects of salt stress in basil (Ocimum basilicum L.) plants.BMC plant biology · 2025Article
- Integrated transcriptome-metabolome analysis reveals oleanolic acid as a central regulator of heat stress adaptation in Rhododendron moulmainense.BMC plant biology · 2025Article
- Melatonin in crop plants: from biosynthesis through pleiotropic effects to enhanced stress resilience.Journal of applied genetics · 2025Review
- Integration of Phytomelatonin Signaling With Jasmonic Acid in Wound-induced Adventitious Root Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Melatonin improves the lead tolerance in Plantago ovata by modulating ROS homeostasis, phytohormone status and expression of stress-responsive genes.Plant cell reports · 2025Article
- Exogenous melatonin delays leaves senescence and enhances saline and alkaline stress tolerance in grape seedlings.Plant signaling & behavior · 2024Article
- Role of Neurotransmitters (Biomediators) in Plant Responses to Stress.Plants (Basel, Switzerland) · 2024Review
- An ecotype-specific effect of osmopriming and melatonin during salt stress in Arabidopsis thaliana.BMC plant biology · 2024Article
- Have All of the Phytohormonal Properties of Melatonin Been Verified?International journal of molecular sciences · 2024Review
- The potential of melatonin and its crosstalk with other hormones in the fight against stress.Frontiers in plant science · 2024Review
- Why did glutamate, GABA, and melatonin become intercellular signalling molecules in plants?eLife · 2023Review
- Effect of Three Boron Concentrations in Soil on Growth and Physiology in Sweet Cherry Trees.Plants (Basel, Switzerland) · 2023Article
- The pathway of melatonin biosynthesis in common wheat (Triticum aestivum).Journal of pineal research · 2023Article
- Exogenous melatonin mediates radish (Frontiers in plant science · 2023Article
- Melatonin and Indole-3-Acetic Acid Synergistically Regulate Plant Growth and Stress Resistance.Cells · 2022Review
- Nitric Oxide Is Essential for Melatonin to Enhance Nitrate Tolerance of Cucumber Seedlings.Molecules (Basel, Switzerland) · 2022Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Melatonin (N-acetyl-5-methoxytryptamine) plays important roles in plant developmental growth, especially in root architecture. The similarity in both chemical structure and biosynthetic pathway suggests a potential linkage between melatonin and auxin signaling. However the molecular mechanism regulating this melatonin-mediated root architecture changes is not yet elucidated. In the present study, we re-analyzed previously conducted transcriptome data and identified 16 auxin-related genes whose expression patterns were altered by treatment with melatonin. Several of these genes encoding important auxin transporters or strongly affecting auxin transport were significantly down regulated. In wild type Arabidopsis, Melatonin inhibited both primary root growth and hypocotyl elongation, but enhanced lateral root development in a dose dependent manner. However, the lateral-root-promoting role of melatonin was abolished when each individual null mutant affecting auxin transport including pin5, wag1, tt4 and tt5, was examined. Furthermore, melatonin acts synergistically with auxin to promote lateral root development in wild type Arabidopsis, but such synergistic effects were absent in knockout mutants of individual auxin transport related genes examined. These results strongly suggest that melatonin enhances lateral root development through regulation of auxin distribution via modulation of auxin transport. A working model is proposed to explain how melatonin and auxin act together to promote lateral root development. The present study deepens our understanding of the relationship between melatonin and auxin signaling in plant species.
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