Evidence map›Paper›PMID 31461375›Full record

ArticleJournal of neurophysiology2019

Visual responses in the dorsal lateral geniculate nucleus at early stages of retinal degeneration in

Christopher A Procyk, Annette E Allen, Franck P Martial, Robert J Lucas

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christopher A ProcykFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.ORCID 0000-0002-6754-4665
Annette E AllenFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Franck P MartialFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Robert J LucasFaculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
University of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inherited retinal degenerations encompass a wide range of diseases that result in the death of rod and cone photoreceptors, eventually leading to irreversible blindness. Low vision survives at early stages of degeneration, at which point it could rely on residual populations of rod/cone photoreceptors as well as the inner retinal photoreceptor, melanopsin. To date, the impact of partial retinal degeneration on visual responses in the primary visual thalamus (dorsal lateral geniculate nucleus, dLGN) remains unknown, as does their relative reliance on surviving rod and cone photoreceptors vs. melanopsin. To answer these questions, we recorded visually evoked responses in the dLGN of anesthetized

Indexed as

Evoked Potentials, VisualAnimalsContrast SensitivityCyclic Nucleotide Phosphodiesterases, Type 6Gamma RhythmGeniculate BodiesMiceMice, Inbred C57BLReaction TimeRetinal Cone Photoreceptor CellsRetinal DegenerationRetinal Rod Photoreceptor CellsVision, OcularCyclic Nucleotide Phosphodiesterases, Type 6cone photoreceptordorsal lateral geniculate nucleusmelanopsinreceptor substitutionretinal degenerationspatial receptive field

Identifiers

PMID31461375
PMCPMC6843091
OpenAlexW2970603885

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.