ArticleAmerican journal of physiology. Cell physiology2019
Molecular mechanism of TMEM16A regulation: role of CaMKII and PP1/PP2A.
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Article in American journal of physiology. Cell physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- TMEM16A channel signalling microdomains in the regulation of vascular function.The Journal of physiology · 2026Review
- Identification of novel TMEM16A blockers through integrated virtual screening, molecular dynamics, and experimental studies.Scientific reports · 2025Article
- The ion channel Anoctamin 10/TMEM16K coordinates organ morphogenesis across scales in the urochordate notochord.PLoS biology · 2024Article
- Effects of Dietary Supplementation with Tea Residue on Growth Performance, Digestibility, and Diarrhea in Piglets.Animals : an open access journal from MDPI · 2024Article
- The conducted vasomotor response and the principles of electrical communication in resistance arteries.Physiological reviews · 2024Review
- Pathophysiology and pathogenic mechanisms of pulmonary hypertension: role of membrane receptors, ion channels, and CaPhysiological reviews · 2023Review
- Discovery of Fungus-Derived Nornidulin as a Novel TMEM16A Inhibitor: A Potential Therapy to Inhibit Mucus Secretion in Asthma.Journal of experimental pharmacology · 2023Article
- Polymodal Control of TMEM16x Channels and Scramblases.International journal of molecular sciences · 2022Review
- Molecular mechanisms of activation and regulation of ANO1-Encoded CaChannels (Austin, Tex.) · 2021Review
- Calmodulin-Dependent Regulation of Overexpressed but Not Endogenous TMEM16A Expressed in Airway Epithelial Cells.Membranes · 2021Article
- Gating and Regulatory Mechanisms of TMEM16 Ion Channels and Scramblases.Frontiers in physiology · 2021Review
- Allosteric modulation of alternatively spliced CaProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Article
- Calcium-Activated Chloride Channel ANO1/TMEM16A: Regulation of Expression and Signaling.Frontiers in physiology · 2020Review
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Ramon J AyonDivision of Translational and Regenerative Medicine, Department of Medicine, College of Medicine, The University of Arizona College of Medicine, Arizona Health Sciences Center, Tucson, Arizona.
Matthew B HawnDepartment of Pharmacology, Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, Nevada.
Joydeep AounDepartment of Pharmacology, Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, Nevada.
Michael WiwcharDepartment of Pharmacology, Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, Nevada.
Abigail S ForrestDepartment of Pharmacology, Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, Nevada.
Fiona CunninghamDepartment of Pharmacology, Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, Nevada.
Cherie A SingerDepartment of Pharmacology, Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, Nevada.
Maria L ValencikDepartment of Pharmacology, Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, Nevada.
Iain A GreenwoodInstitute of Molecular and Clinical Sciences, St. George's University of London, London, United Kingdom.
Normand LeblancDepartment of Pharmacology, Center of Biomedical Research Excellence for Molecular and Cellular Signal Transduction in the Cardiovascular System, University of Nevada, Reno School of Medicine, Reno, Nevada.
University of Nevada, Reno · USSt George's, University of London · GBUniversity of Arizona · US
Funding
Transgenic Animal Genotyping and Phenotyping CoreP20GM130459 · NIGMS · UNIVERSITY OF NEVADA RENO · PI Mitchell Hamed Omar · 2019 to 2026
$20.3MSignal transduction pathways regulated by cell volumeP20RR015581 · NCRR · UNIVERSITY OF NEVADA RENO · PI BRITTON, FIONA CATHERINE · 2000 to 2009
$19.5MRole of ANO1 Channels and Its Regulation by PIP2 in EC-Coupling in Pulmonary Artery MyocytesR01HL146054 · NHLBI · UNIVERSITY OF NEVADA RENO · PI EARLEY, SCOTT, LEBLANC, NORMAND · 2019 to 2022
$2.0MBestrophin Channel Function in HeartR01HL091238 · NHLBI · UNIVERSITY OF NEVADA RENO · PI BRITTON, FIONA CATHERINE · 2008 to 2012
$2.0MProperties of Clca Channels in Vascular MyocytesR01HL075477 · NHLBI · UNIVERSITY OF NEVADA RENO · PI LEBLANC, NORMAND · 2005 to 2009
$1.7MmicroRNA-25 attenuates allergic inflammation by altering airway smooth muscle phenotype and functionR01HL127192 · NHLBI · UNIVERSITY OF NEVADA RENO · PI SINGER, CHERIE · 2016 to 2019
$1.5MRegulation of Calcium-activated Chloride Conductance in Smooth Muscle VasculatureF31HL090023 · NHLBI · UNIVERSITY OF NEVADA RENO · PI AYON, RAMON JOSE · 2007 to 2011
$110kBritish Heart Foundation PG/14/57/30992NCRR NIH HHS P20 RR015581NHLBI NIH HHS F31 HL090023NHLBI NIH HHS R01 HL075477NHLBI NIH HHS R01 HL091238NHLBI NIH HHS R01 HL127192NHLBI NIH HHS R01 HL146054NIGMS NIH HHS P20 GM130459
Abstract
This study explored the mechanism by which Ca
Indexed as
Gene Expression RegulationAdenosine TriphosphateAmino Acid SequenceAnimalsAnoctamin-1BenzenesulfonamidesBenzylaminesCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CantharidinChloridesEvoked PotentialsHEK293 CellsHumansIon TransportMiceAdenosine TriphosphateANO1 protein, humanANO1 protein, mouseAnoctamin-1BenzenesulfonamidesBenzylaminesCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CaMKII inhibitor AIPCantharidinChloridesKN 93Neoplasm ProteinsOkadaic AcidPeptidesProtein Phosphatase 1Protein Phosphatase 2SulfonamidesAno-1calcium-activated chloride channelCaMKIIregulationTMEM16A
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Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.