Evidence map›Paper›PMID 31460967›Full record

ArticlePsychosomatic medicine2019

Fine Particle Air Pollution and Physiological Reactivity to Social Stress in Adolescence: The Moderating Role of Anxiety and Depression.

Jonas G Miller, Julia S Gillette, Erika M Manczak, Katharina Kircanski, Ian H Gotlib

Abstract read
In one paragraph

Article in Psychosomatic medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. PMiScience · 2026
    Review
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  19. Examining air pollution (PMScientific reports · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonas G MillerFrom the Department of Psychiatry and Behavioral Sciences (Miller), School of Medicine, and Department of Psychology (Gillett, Gotlib), Stanford University, California; Department of Psychology (Manczak), University of Denver, Colorado; and Emotion and Development Branch, National Institute of Mental Health (Kircanski), Bethesda, Maryland.
Julia S Gillette
Erika M Manczak
Katharina Kircanski
Ian H Gotlib

Funding

A BIOBEHAVIORAL RESEARCH TRAINING PROGRAMT32MH019938 · NIMH · STANFORD UNIVERSITY · PI Corey J Keller, RACHEL MANBER · 1994 to 2026
$9.4M
Psychobiological Mechanisms Underlying the Association Between Early Life Stress and Depression Across AdolescenceR37MH101495 · NIMH · STANFORD UNIVERSITY · PI IAN H GOTLIB · 2018 to 2026
$6.6M
TRAINING FOR CHILD PSYCHIATRY AND CHILD DEVELOPMENTT32MH019908 · NIMH · STANFORD UNIVERSITY · PI IAN H GOTLIB, DAVID S HONG · 1993 to 2026
$6.3M
The Effects of Early Life Stress on Neurodevelopment in Children and AdolescentsR01MH101495 · NIMH · STANFORD UNIVERSITY · PI GOTLIB, IAN H · 2013 to 2016
$2.9M
Stress Depression and Anxiety - An Integrative Psychobiological InvestigationF32MH096385 · NIMH · STANFORD UNIVERSITY · PI KIRCANSKI, KATHARINA · 2012 to 2014
$150k
NIMH NIH HHS F32 MH096385NIMH NIH HHS R01 MH101495NIMH NIH HHS R37 MH101495NIMH NIH HHS T32 MH019908NIMH NIH HHS T32 MH019938
6 · The paper itself

Abstract

objectiveExposure to high levels of fine particle air pollution (PM2.5) is associated with adolescent pathophysiology. It is unclear, however, if PM2.5 is associated with physiology within psychosocial contexts, such as social stress, and whether some adolescents are particularly vulnerable to PM2.5-related adverse effects. This study examined the association between PM2.5 and autonomic reactivity to social stress in adolescents and tested whether symptoms of anxiety and depression moderated this association.

methodsAdolescents from Northern California (N = 144) participated in a modified Trier Social Stress Test while providing high-frequency heart rate variability and skin conductance level data. PM2.5 data were recorded from CalEnviroScreen. Adolescents reported on their own symptoms of anxiety and depression using the Youth Self-Report, which has been used in prior studies and has good psychometric properties (Cronbach's α in this sample was .86).

resultsAdolescents residing in neighborhoods characterized by higher concentrations of PM2.5 demonstrated greater autonomic reactivity (i.e., indexed by lower heart rate variability and higher skin conductance level) (β = .27; b = .44, p = .001, 95% CI = 0.19 to 0.68) in response to social stress; this association was not accounted for by socioeconomic factors. In addition, adolescents who reported more severe anxiety and depression symptoms showed the strongest association between PM2.5 and autonomic reactivity to social stress (β = .53; b = .86, p < .001, 95% CI = 0.48 to 1.23).

conclusionsExposure to PM2.5 may heighten adolescent physiological reactivity to social stressors. Moreover, adolescents who experience anxiety and depression may be particularly vulnerable to the adverse effects of PM2.5 on stress reactivity.

Indexed as

Social BehaviorAdolescentAir PollutionAnxietyAutonomic Nervous SystemCaliforniaChildDepressionFemaleHumansMaleParticulate MatterStress, PsychologicalParticulate Matter

Identifiers

PMID31460967
PMCPMC6716517

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.