ArticleMedicine and pharmacy reports2019
The economic burden of constipation therapy.
Article in Medicine and pharmacy reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Nutritional knowledge, fiber intake, body mass index, and sex associated with constipation symptoms in Peruvian adults.Scientific reports · 2025Article
- Observational
- Article
- Causal relationship between gut microbiota and constipation: a bidirectional Mendelian randomization study.Frontiers in microbiology · 2024Article
- Parents' Knowledge, Attitude, and Practice Related to Childhood Constipation in Makkah, Saudi Arabia.Cureus · 2024Article
- Background factors involved in the epidemiology of functional constipation in the Japanese population: a cross-sectional study.BioPsychoSocial medicine · 2022Article
- Bisacodyl: A review of pharmacology and clinical evidence to guide use in clinical practice in patients with constipation.Neurogastroenterology and motility · 2021Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimConstipation is a widespread condition that requires adequate therapy. Given the large use of laxatives, it is important to know the burden of the treatment of this condition on the healthcare budget.
methodsWe collected information on the number of therapeutic units (boxes) of five frequently used laxatives delivered by prescription or over the counter in 30 pharmacies randomly selected in two adjacent counties from Romania for two consecutive years. We calculated also the cost value of the laxatives delivered.
resultsThe total cost of laxatives in the group of pharmacies investigated was on average 62,500 euros per year. We extrapolated that the laxative consumption in Romania should be over 15 million Euro.
conclusionsTo our knowledge this is the first study on the burden of constipation in this country. Although therapeutic units of laxatives are not expensive, the wide use of these drugs represents an economic burden for the patient.
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Registered trials
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