Evidence map›Paper›PMID 31460363›Full record

ArticleACS omega2019

Click Chemistry in the Design and Production of Hybrid Tracers.

Albertus W Hensbergen, Danny M van Willigen, Mick M Welling, Felicia A van der Wijk, Clarize M de Korne, Matthias N van Oosterom, Margret Schottelius, Hans-Jürgen Wester, Tessa Buckle, Fijs W B van Leeuwen

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. More Than a Glow: How Cyanine Dyes Shape Tracer Pharmacokinetics.Angewandte Chemie (International ed. in English) · 2026
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  5. The helminth glycoprotein omega-1 improves metabolic homeostasis in obese mice through type 2 immunity-independent inhibition of food intake.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Albertus W HensbergenInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
Danny M van WilligenInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
Mick M WellingInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
Felicia A van der WijkInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
Clarize M de KorneInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
Matthias N van OosteromInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
Margret SchotteliusPharmaceutical Radiochemistry, Technische Universität München, Garching 85748, Germany.
Hans-Jürgen WesterPharmaceutical Radiochemistry, Technische Universität München, Garching 85748, Germany.
Tessa BuckleInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
Fijs W B van LeeuwenInterventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden 2333 ZA, The Netherlands.
Leiden University Medical Center · NLTechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hybrid tracers containing both fluorescent and radioactive imaging labels have demonstrated clinical potential during sentinel lymph node procedures. To combine these two labels on a single targeting vector that allows tumor-targeted imaging, end-labeling strategies are often applied. For α

Identifiers

PMID31460363
PMCPMC6682143
OpenAlexW2963395535

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.