Evidence map›Paper›PMID 31460170›Full record

ArticleACS omega2019

Self-Assembly of Diphenylalanine-Peptide Nucleic Acid Conjugates.

Dhrubajyoti Datta, Omshanker Tiwari, Manoj Kumar Gupta

Abstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Morphology and Applications of Self-Assembled Peptide Nucleic Acids.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dhrubajyoti DattaDepartment of Chemistry, Chemical Biology Unit, Indian Institute of Science Education and Research Pune, Dr. Homi Bhabha Road, Pune 411008, India.
Omshanker TiwariDepartment of Chemistry, Chemical Biology Unit, Indian Institute of Science Education and Research Pune, Dr. Homi Bhabha Road, Pune 411008, India.
Manoj Kumar GuptaDepartment of Chemistry, Chemical Biology Unit, Indian Institute of Science Education and Research Pune, Dr. Homi Bhabha Road, Pune 411008, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The synthesis and self-assembled nanostructures of a series of nucleopeptides (NPs) derived from the dipeptide Phe-Phe and the peptide nucleic acid unit which are covalently attached through an amide or a triazole linker are described. Depending on the variables such as protecting groups, linkers, and nucleobases, spherical nanoparticles were observed through scanning electron microscopy and high-resolution transmission electron microscopy images, and the porous nature of representative NPs was corroborated by carboxyfluorescein entrapment. Hydrophobic substituents on different sites of NPs and solvents employed for peptide self-assembly played a crucial role for corresponding morphologies. The stability of nanoparticles was also probed under external stimuli such as pH, temperature, and enzymatic hydrolysis using proteolytic enzymes. The semiconducting nature of the NP-modified carbon electrodes suggested their potential use as a new capacitor material.

Identifiers

PMID31460170
PMCPMC6649282

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.