Evidence map›Paper›PMID 31460163›Full record

ArticleACS omega2019

Radiofrequency Hyperthermia of Cancer Cells Enhanced by Silicic Acid Ions Released During the Biodegradation of Porous Silicon Nanowires.

Maxim Gongalsky, Georgii Gvindzhiliia, Konstantin Tamarov, Olga Shalygina, Alexander Pavlikov, Valery Solovyev, Andrey Kudryavtsev, Vladimir Sivakov, Liubov A Osminkina

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Nanoparticle-Mediated Hyperthermia and Cytotoxicity Mechanisms in Cancer.International journal of molecular sciences · 2023
    Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Maxim GongalskyDepartment of Physics, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Georgii GvindzhiliiaDepartment of Physics, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Konstantin TamarovDepartment of Physics, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Olga ShalyginaDepartment of Physics, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Alexander PavlikovDepartment of Physics, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Valery SolovyevInstitute of Theoretical and Experimental Biophysics, Russian Academy of Science, Pushchino, 142290 Moscow Region, Russia.
Andrey KudryavtsevInstitute of Theoretical and Experimental Biophysics, Russian Academy of Science, Pushchino, 142290 Moscow Region, Russia.
Vladimir SivakovLeibniz Institute of Photonic Technology, Jena 07745, Germany.
Liubov A OsminkinaDepartment of Physics, Lomonosov Moscow State University, Leninskie Gory 1, 119991 Moscow, Russia.
Lomonosov Moscow State University · RUInstitute of Theoretical and Experimental Biophysics · RULeibniz Institute of Photonic Technology · DEUniversity of Eastern Finland · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The radiofrequency (RF) mild hyperthermia effect sensitized by biodegradable nanoparticles is a promising approach for therapy and diagnostics of numerous human diseases including cancer. Herein, we report the significant enhancement of local destruction of cancer cells induced by RF hyperthermia in the presence of degraded low-toxic porous silicon (PSi) nanowires (NWs). Proper selection of RF irradiation time (10 min), intensity, concentration of PSi NWs, and incubation time (24 h) decreased cell viability to 10%, which can be potentially used for cancer treatment. The incubation for 24 h is critical for degradation of PSi NWs and the formation of silicic acid ions H

Identifiers

PMID31460163
PMCPMC6648043
OpenAlexW2953080170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.