Consequences of Hydrophobic Nanotube Binding on the Functional Dynamics of Signaling Protein Calmodulin.

Wentao Zhu, Jianyang Kong, Jian Zhang, Jun Wang, Wenfei Li, Wei Wang

Open access · goldAbstract read

In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.3field-weighted citation impact, top 51% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

Unbiased Enhanced Sampling in Molecular Dynamics via Simultaneously Accelerating Diffusion in Multiple Low-Dimensional Collective Variable Spaces.Journal of chemical theory and computation · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wentao ZhuNational Laboratory of Solid State Microstructure, and Collaborative Innovation Center of Advanced Microstructures and Department of Physics, Nanjing University, Nanjing 210093, China.

Jianyang KongNational Laboratory of Solid State Microstructure, and Collaborative Innovation Center of Advanced Microstructures and Department of Physics, Nanjing University, Nanjing 210093, China.

Jian ZhangNational Laboratory of Solid State Microstructure, and Collaborative Innovation Center of Advanced Microstructures and Department of Physics, Nanjing University, Nanjing 210093, China.

Jun WangNational Laboratory of Solid State Microstructure, and Collaborative Innovation Center of Advanced Microstructures and Department of Physics, Nanjing University, Nanjing 210093, China.

Wenfei LiNational Laboratory of Solid State Microstructure, and Collaborative Innovation Center of Advanced Microstructures and Department of Physics, Nanjing University, Nanjing 210093, China.

Wei WangNational Laboratory of Solid State Microstructure, and Collaborative Innovation Center of Advanced Microstructures and Department of Physics, Nanjing University, Nanjing 210093, China.

Collaborative Innovation Center of Advanced Microstructures · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The wide applications of nanomaterials in industry and our daily life have raised growing concerns on their toxicity to human body. Increasing evidence links the cytotoxicity of nanoparticles to the disruption of cellular signaling pathways. Here, we report a computational study on the mechanisms of the cytotoxicity of carbon nanotubes (CNTs) by investigating the direct impacts of CNTs on the functional motions of calmodulin (CaM), which is one of the most important signaling proteins in a cell, and its signaling function relies on the Ca

Identifiers

PMID31460146

DOI10.1021/acsomega.9b01217

PMCPMC6648716

OpenAlexW2951940409

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.