Evidence map›Paper›PMID 31460025›Full record

ArticleACS omega2019

Mitochondria-Targeted New Blue Light-Emitting Fluorescent Molecular Probe.

Saswat Mohapatra, Gaurav Das, Chirantan Kar, Masashi Nitani, Yutaka Ie, Yoshio Aso, Surajit Ghosh

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Saswat MohapatraOrganic and Medicinal Chemistry Division, Structural Biology and Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, West Bengal, India.
Gaurav DasOrganic and Medicinal Chemistry Division, Structural Biology and Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, West Bengal, India.
Chirantan KarOrganic and Medicinal Chemistry Division, Structural Biology and Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, West Bengal, India.
Masashi NitaniThe Institute of Scientific and Industrial Research Osaka University, 8-1, Mihogaoka, Osaka 567-0047, Ibaraki, Japan.
Yutaka IeThe Institute of Scientific and Industrial Research Osaka University, 8-1, Mihogaoka, Osaka 567-0047, Ibaraki, Japan.
Yoshio AsoThe Institute of Scientific and Industrial Research Osaka University, 8-1, Mihogaoka, Osaka 567-0047, Ibaraki, Japan.
Surajit GhoshOrganic and Medicinal Chemistry Division, Structural Biology and Bioinformatics Division, CSIR-Indian Institute of Chemical Biology, 4 Raja S. C. Mullick Road, Jadavpur, Kolkata 700032, West Bengal, India.
Indian Institute of Chemical Biology · INThe University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Discovery of a nontoxic fluorescent molecular probe to "light up" specific cellular organelles is extremely essential to understand dynamics of intracellular components. Here, we report a new nontoxic mitochondria-targeted linear bithiazole compound, containing trifluoroacetyl terminal groups, which emits intense blue fluorescence and stained mitochondria of various cells. Interestingly, the power of fluorescence is completely off when the bithiazole unit is stapled by a carbonyl bridge.

Identifiers

PMID31460025
PMCPMC6649077
OpenAlexW2947641014

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.