ArticleACS omega2018
Fabrication of Three-Dimensional Scaffolds Based on Nano-biomimetic Collagen Hybrid Constructs for Skin Tissue Engineering.
Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Advances in Engineering Human Tissue Models.Frontiers in bioengineering and biotechnology · 2020Pooled it
- Transformative bioprinting: 4D printing and its role in the evolution of engineering and personalized medicine.Discover nano · 2025Review
- Fibroblasts/three-dimensional scaffolds complexes promote wound healing in rats with skin defects.Tissue barriers · 2025Article
- Synergistic effect of chitosan-alginate composite hydrogel enriched with ascorbic acid and alpha-tocopherol under hypoxic conditions on the behavior of mesenchymal stem cells for wound healing.Stem cell research & therapy · 2023Article
- Biomolecular and cellular effects in skin wound healing: the association between ascorbic acid and hypoxia-induced factor.Journal of biological engineering · 2023Review
- Preparation and characterization of propolis reinforced eggshell membrane/ GelMA composite hydrogel for biomedical applications.BMC biotechnology · 2023Article
- Development of Scaffolds from Bio-Based Natural Materials for Tissue Regeneration Applications: A Review.Gels (Basel, Switzerland) · 2023Review
- Additive Manufacturing of Biomaterials-Design Principles and Their Implementation.Materials (Basel, Switzerland) · 2022Review
- Degradable allylRSC advances · 2021Article
- Milestones and current achievements in development of multifunctional bioscaffolds for medical application.Bioactive materials · 2021Review
- Novel hybrid polyester-polyacrylate hydrogels enriched with platelet-derived growth factor for chondrogenic differentiation of adipose-derived mesenchymal stem cells in vitro.Journal of biological engineering · 2021Article
- Preparation and characterization of novel anti-inflammatory biological agents based on piroxicam-loaded poly-ε-caprolactone nano-particles for sustained NSAID delivery.Drug delivery · 2020Article
- Graphene Oxide-Induced Interfacial Transcrystallization of Single-Fiber Milkweed/Polycaprolactone/Polyvinylchloride Composites.ACS omega · 2020Article
- Cartilage tissue engineering for craniofacial reconstruction.Archives of plastic surgery · 2020Article
- Electroconductive Nanobiomaterials for Tissue Engineering and Regenerative Medicine.Bioelectricity · 2020Review
- Status of Plant Protein-Based Green Scaffolds for Regenerative Medicine Applications.Biomolecules · 2019Review
- Scaffolding Strategies for Tissue Engineering and Regenerative Medicine Applications.Materials (Basel, Switzerland) · 2019Review
- An overview of advanced biocompatible and biomimetic materials for creation of replacement structures in the musculoskeletal systems: focusing on cartilage tissue engineering.Journal of biological engineering · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Three-dimensional (3D) biodegradable and biomimetic porous scaffolds are ideal frameworks for skin tissue engineering. In this study, hybrid constructs of 3D scaffolds were successfully fabricated by the freeze-drying method from combinations of the type I collagen (Col) and synthetic poly(lactic acid) (PLLA) or polycaprolactone (PCL). Four different groups of 3D porous scaffolds including PCL, PCL-Col, PCL-PLLA, and PCL-PLLA-Col were fabricated and systematically characterized by hydrogen nuclear magnetic resonance, Fourier transform infrared spectroscopy, and scanning electron microscopy (SEM). Adipose tissue-derived mesenchymal stem cells (AT-MSCs) were seeded in all scaffolds, and the viability, proliferation, and adhesion of the cells were investigated using dimethylthiazol diphenyltetrazolium bromide assay and SEM. The results showed that scaffolds containing Col, particularly PCL-PLLA-Col scaffold, with pore sizes close to 400 nm and being sufficiently interconnected, have significantly greater potential (
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.