Evidence map›Paper›PMID 31458837›Full record

ArticleACS omega2018

Selective Screening of Biological Thiols by Means of an Unreported Magenta Interaction and Evaluation Using Smartphones.

Francisco J Ortega-Higueruelo, Fernando Langa

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Francisco J Ortega-HiguerueloInstituto de Nanociencia, Nanotecnología y Materiales Moleculares (INAMOL), Universidad de Castilla-La Mancha, Avda. Carlos III s/n, Toledo 45071, Spain.
Fernando LangaInstituto de Nanociencia, Nanotecnología y Materiales Moleculares (INAMOL), Universidad de Castilla-La Mancha, Avda. Carlos III s/n, Toledo 45071, Spain.
University of Castilla-La Mancha · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The determination of biological thiols is considered to be of great interest because of the participation of these molecules in physiological disorders as indicators of their existence and progress, such as Alzheimer's disease, cancer, and cystic fibrosis, among others. Optical techniques for the quantification of these analytes are superior to other techniques in terms of selectivity, sensitivity, and cost. We describe here a simple protocol to determine biological thiols by means of a colorimetric analysis based on a magenta color interaction with 5,5'-dithiobis(2-nitrobenzoic acid). This methodology leverages the technology developed in smartphones, and it can be transferred to a simple analytical procedure through the use of absorbent strips and a cell phone. Excellent characteristics were observed, and this method opens up alternative avenues for the detection of biological thiols in a very simple and portable manner.

Identifiers

PMID31458837
PMCPMC6644678
OpenAlexW2808863533

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.