Evidence map›Paper›PMID 31458749›Full record

ArticleACS omega2018

One-Pot Tandem Approach to Functionalized 3-Hydroxy-2-furanyl-acrylamides.

Nagaraju Mupparapu, Shahnawaz Khan, Pankaj Bandhoria, Shunmuganarayanan Athimoolam, Qazi Naveed Ahmed

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nagaraju MupparapuMedicinal Chemistry Division, Indian Institute of Integrative Medicine (IIIM), Jammu 180001, India.
Shahnawaz KhanMedicinal Chemistry Division, Indian Institute of Integrative Medicine (IIIM), Jammu 180001, India.
Pankaj BandhoriaDepartment of Physics, GGM Science College, Jammu 180001, India.
Shunmuganarayanan AthimoolamDepartment of Physics, University College of Engineering Nagercoil, Anna University of Technology Tirunelveli, Nagercoil 629 004, India.
Qazi Naveed AhmedMedicinal Chemistry Division, Indian Institute of Integrative Medicine (IIIM), Jammu 180001, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel one-pot tandem process involving Knoevenagel condensation, Michael addition, selective amidation, and Paal-Knorr cyclization to diverse functionalized 3-hydroxy-2-furanyl-acrylamides from simple 2-oxoaldehydes and aroylacetonitriles was presented. Attempts were also made to expand the scope of the reaction to different 2-heteroarylfurans. The packing diagram of the molecules viewed down along the α-axis of the unit cell showed a characteristic intramolecular classical O-H···O hydrogen bond between hydroxyl and carbonyl O atoms leading to self-associated (

Identifiers

PMID31458749
PMCPMC6641926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.