Evidence map›Paper›PMID 31458733›Full record

ArticleACS omega2018

Impact of Pore-Walls Ligand Assembly on the Biodegradation of Mesoporous Organosilica Nanoparticles for Controlled Drug Delivery.

Haneen Omar, Basem Moosa, Kholod Alamoudi, Dalaver H Anjum, Abdul-Hamid Emwas, Omar El Tall, Binh Vu, Fuyu Tamanoi, Abdulaziz AlMalik, Niveen M Khashab

Abstract read
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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  7. Review
  8. Using NMR spectroscopy to investigate the role played by copper in prion diseases.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Review
  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Haneen OmarSmart Hybrid Materials Laboratory, Advanced Membranes, and Porous Materials Center, King Abdullah University of Science and Technology, Thuwal 23955-6900, Saudi Arabia.
Basem MoosaSmart Hybrid Materials Laboratory, Advanced Membranes, and Porous Materials Center, King Abdullah University of Science and Technology, Thuwal 23955-6900, Saudi Arabia.
Kholod AlamoudiSmart Hybrid Materials Laboratory, Advanced Membranes, and Porous Materials Center, King Abdullah University of Science and Technology, Thuwal 23955-6900, Saudi Arabia.
Dalaver H AnjumKing Abdullah University of Science and Technology (KAUST), Core Labs, Thuwal 23955-6900, Saudi Arabia.
Abdul-Hamid EmwasKing Abdullah University of Science and Technology (KAUST), Core Labs, Thuwal 23955-6900, Saudi Arabia.
Omar El TallKing Abdullah University of Science and Technology (KAUST), Core Labs, Thuwal 23955-6900, Saudi Arabia.
Binh VuDepartment of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, Molecular Biology Institute, University of California, Los Angeles, California 90095-1489, United States.
Fuyu TamanoiDepartment of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, Molecular Biology Institute, University of California, Los Angeles, California 90095-1489, United States.
Abdulaziz AlMalikLife Sciences and Environment Research Institute, Center of Excellence in Nanomedicine (CENM), King Abdulaziz City for Science and Technology (KACST), Riyadh 11461, Saudi Arabia.
Niveen M KhashabSmart Hybrid Materials Laboratory, Advanced Membranes, and Porous Materials Center, King Abdullah University of Science and Technology, Thuwal 23955-6900, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porous materials with molecular-scale ordering have attracted major attention mainly because of the possibility to engineer their pores for selective applications. Periodic mesoporous organosilica is a class of hybrid materials where self-assembly of the organic linkers provides a crystal-like pore wall. However, unlike metal coordination, specific geometries cannot be predicted because of the competitive and dynamic nature of noncovalent interactions. Herein, we study the influence of competing noncovalent interactions in the pore walls on the biodegradation of organosilica frameworks for drug delivery application. These results support the importance of studying self-assembly patterns in hybrid frameworks to better engineer the next generation of dynamic or "soft" porous materials.

Identifiers

PMID31458733
PMCPMC6641955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.