Evidence map›Paper›PMID 31458155›Full record

ArticleACS omega2018

Synthesis and Characterization of Partially and Fully Saturated Menaquinone Derivatives.

Jordan T Koehn, Dean C Crick, Debbie C Crans

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Allosteric regulation of menaquinone (vitamin KThe Journal of biological chemistry · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jordan T KoehnChemistry Department, Cell and Molecular Biology Program, and Microbiology, Immunology, and Pathology Department, Colorado State University, Fort Collins, Colorado 80523, United States.
Dean C CrickChemistry Department, Cell and Molecular Biology Program, and Microbiology, Immunology, and Pathology Department, Colorado State University, Fort Collins, Colorado 80523, United States.
Debbie C CransChemistry Department, Cell and Molecular Biology Program, and Microbiology, Immunology, and Pathology Department, Colorado State University, Fort Collins, Colorado 80523, United States.
Colorado State University · US

Funding

Unraveling the Origin of Pyrazinamide's Synergy with other anti-TB DrugsR21AI119567 · NIAID · COLORADO STATE UNIVERSITY · PI CRICK, DEAN C · 2015 to 2016
$408k
NIAID NIH HHS R21 AI119567
6 · The paper itself

Abstract

Menaquinones (MKs) contain both a redox active quinone moiety and a hydrophobic repeating isoprenyl side chain of varying lengths and degrees of saturation. This characteristic structure allows MKs to play a key role in the respiratory electron transport system of some prokaryotes by shuttling electrons and protons between membrane-bound protein complexes, which act as electron acceptors and donors. Hydrophobic MK molecules with partially and fully saturated isoprenyl side chains are found in a wide range of eubacteria and archaea, and the structural variations of the MK analogues are evolutionarily conserved but poorly understood. For example,

Identifiers

PMID31458155
PMCPMC6643618
OpenAlexW2899842588

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.