Evidence map›Paper›PMID 31457109›Full record

ArticleBioprinting (Amsterdam, Netherlands)2019

Scaffold-free bioprinting of mesenchymal stem cells using the Regenova printer: Spheroid characterization and osteogenic differentiation.

Izath Nizeet Aguilar, David J Olivos, Alexander Brinker, Marta B Alvarez, Lester J Smith, Tien-Min Gabriel Chu, Melissa A Kacena, Diane R Wagner

Open access · greenAbstract read
In one paragraph

Article in Bioprinting (Amsterdam, Netherlands), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  7. Article
  8. Engineering Spatiotemporal Control in Vascularized Tissues.Bioengineering (Basel, Switzerland) · 2022
    Review
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  11. Article
  12. Article
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  18. Article
  19. Machine intelligence for nerve conduit design and production.Journal of biological engineering · 2020
    Review
  20. The potential role of 3D-bioprinting in xenotransplantation.Current opinion in organ transplantation · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Izath Nizeet AguilarDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
David J OlivosDepartment of Biochemistry and Molecular Biology, Indiana University of School of Medicine, Indianapolis, IN, USA.
Alexander BrinkerDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Marta B AlvarezDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Lester J SmithDepartment of Radiology and Imaging Sciences, Indiana University of School of Medicine, Indianapolis, IN, USA.
Tien-Min Gabriel ChuDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Melissa A KacenaDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Diane R WagnerDepartment of Orthopaedic Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Indiana University – Purdue University Indianapolis · USIndiana University School of Medicine

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
REGULATION OF HEMATOPOIETIC CELL PRODUCTIONT32DK007519 · NIDDK · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI KAPLAN, MARK H · 1986 to 2020
$7.1M
Comprehensive Training Program in Musculoskeletal ResearchT32AR065971 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI ALEXANDER G ROBLING · 2015 to 2026
$4.4M
Photo-Initiated Cartilage Crosslinking as a Preventative for Post-Traumatic OsteoarthritisR01AR069657 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI WAGNER, DIANE · 2016 to 2020
$1.3M
Regenova Bio 3D PrinterS10OD023595 · OD · INDIANA UNIVERSITY INDIANAPOLIS · PI SMITH, LESTER J. · 2017 to 2017
$450k
NCATS NIH HHS UL1 TR001108NIAMS NIH HHS R01 AR069657NIAMS NIH HHS T32 AR065971NIDDK NIH HHS T32 DK007519NIH HHS S10 OD023595
6 · The paper itself

Abstract

Limitations in scaffold material properties, such as sub-optimal degradation time, highlight the need for alternative approaches to engineer

Indexed as

BioprintingMesenchymal stem cellsOsteogenesisRegenovaScaffold-freeSpheroid formationTissue engineering

Identifiers

PMID31457109
PMCPMC6711199
OpenAlexW2942389051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.