ArticleLanguage, cognition and neuroscience2019
Resting-state and Vocabulary Tasks Distinctively Inform On Age-Related Differences in the Functional Brain Connectome.
Article in Language, cognition and neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Functional and effective EEG connectivity patterns in Alzheimer's disease and mild cognitive impairment: a systematic review.Frontiers in aging neuroscience · 2025Pooled it
- Frontal Vulnerability versus Temporal Resilience within the Core Language Network: Neuro-compensatory Mechanisms Underline Differential Language Aging Trajectories.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- The association between amyloid-beta deposition on dual-task gait performance is partially moderated by cognitive functions in healthy older adults.Scientific reports · 2025Article
- Task difficulty modulates age-related differences in functional connectivity during word production.Brain and language · 2023Article
- Resting State Network Segregation Modulates Age-Related Differences in Language Production.Neurobiology of language (Cambridge, Mass.) · 2023Article
- Changes in Default Mode Network Connectivity in Resting-State fMRI in People with Mild Dementia Receiving Cognitive Stimulation Therapy.Brain sciences · 2021Article
- The intensity and connectivity of spontaneous brain activity in a language network relate to aging and language.Neuropsychologia · 2021Article
- Stronger right hemisphere functional connectivity supports executive aspects of language in older adults.Brain and language · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
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Abstract
Most of the current knowledge about age-related differences in brain neurofunctional organization stems from neuroimaging studies using either a "resting state" paradigm, or cognitive tasks for which performance decreases with age. However, it remains to be known if comparable age-related differences are found when participants engage in cognitive activities for which performance is maintained with age, such as vocabulary knowledge tasks. A functional connectivity analysis was performed on 286 adults ranging from 18 to 80 years old, based either on a resting state paradigm or when engaged in vocabulary tasks. Notable increases in connectivity of regions of the language network were observed during task completion. Conversely, only age-related decreases were observed across the whole connectome during resting-state. While vocabulary accuracy increased with age, no interaction was found between functional connectivity, age and task accuracy or proxies of cognitive reserve, suggesting that older individuals typically benefits from semantic knowledge accumulated throughout one's life trajectory, without the need for compensatory mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.