Evidence map›Paper›PMID 31457020›Full record

ArticleIranian journal of biotechnology2018

Molecular Engineering of the

Ibrahim Torktaz, Jafar Hemmat, Ali Asghar Karkhane, Garshasb Rigi, Amin Rostami, Jafar Khezri, Reza Behroozi

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ibrahim TorktazNational Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
Jafar HemmatBiotechnology Department. Iranian Research Organization for Science and Technology (IROST) Tehran-Iran.
Ali Asghar KarkhaneNational Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
Garshasb RigiDepartment of Genetics, Faculty of Basic Science, University of Shahrekord, Shahrekord, Iran.
Amin RostamiDepartment of Basic Sciences, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Jafar KhezriNational Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
Reza BehrooziNational Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
National Institute of Genetic Engineering and Biotechnology · IRShahid Beheshti University of Medical Sciences · IRShahrekord University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundConsidering natural thermal stability,

objectivesUsing MATERIALS AND

methodsIn this study we predicted the 3D structure of the enzymes, then simulated the molecular docking study using MolDock, PLANTS, and Lamarkian genetic algorithm as scoring functions for the docking and in silico engineering of the protein aiming to increase the thermal stability and catalytic activity.

resultsA series of thermal stability increasing point mutations were exerted around the active site of the enzyme, then by docking procedure, the binding affinity was measured and finally a list of mutations which theoretically improved the increased thermal stability as well as catalytic activity were proposed.

conclusionsBased on the

Indexed as

AmylaseCatalytic activityCel5EGeobacillus stearothermophilusIndustryThermal stability

Identifiers

PMID31457020
PMCPMC6697822
OpenAlexW2888995400

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.