Evidence map›Paper›PMID 31456953›Full record

ArticleFrontiers in cellular and infection microbiology2019

Assessing the Contribution of an HtrA Family Serine Protease During

Clay D Jackson-Litteken, Amanda K Zalud, C Tyler Ratliff, Jacob I Latham, Travis J Bourret, Job E Lopez, Jon S Blevins

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Endogenous and Borrowed Proteolytic Activity in theMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  4. Article
  5. Genetic Manipulation ofCurrent issues in molecular biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Clay D Jackson-LittekenDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Amanda K ZaludDepartment of Medical Microbiology and Immunology, Creighton University, Omaha, NE, United States.
C Tyler RatliffDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Jacob I LathamDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Travis J BourretDepartment of Medical Microbiology and Immunology, Creighton University, Omaha, NE, United States.
Job E LopezSection of Tropical Medicine, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, United States.
Jon S BlevinsDepartment of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
University of Arkansas for Medical Sciences · USCreighton University · USBaylor College of Medicine · US

Funding

Study of the Cell-specific Inflammasome Responses During Defense Against Gram-negative BacteriaP20GM103625 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI SMELTZER, MARK S · 2012 to 2021
$21.5M
Pilot Grant ProgramP30GM145393 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI MARK S SMELTZER · 2022 to 2026
$7.6M
Identification of essential factors contributing to vector colonization and transmission of relapsing fever spirochetesR01AI137412 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI LOPEZ, JOB E · 2018 to 2022
$2.0M
Rrp2-dependent gene regulation in Borrelia burgdorferiR21AI119532 · NIAID · UNIV OF ARKANSAS FOR MED SCIS · PI BLEVINS, JON SCOTT · 2015 to 2016
$403k
NIAID NIH HHS R01 AI137412NIAID NIH HHS R21 AI119532NIGMS NIH HHS P20 GM103625NIGMS NIH HHS P30 GM145393
6 · The paper itself

Abstract

Tick-borne relapsing fever (TBRF), characterized by recurring febrile episodes, is globally distributed and among the most common bacterial infections in some African countries. Despite the public health concern that this disease represents, little is known regarding the virulence determinants required by TBRF

Indexed as

Animal DiseasesAnimalsBacterial ProteinsBody TemperatureBorreliaGene Expression Regulation, BacterialHot TemperatureMammalsMiceMutationOperonOxidative StressProteomicsRelapsing FeverSerine EndopeptidasesBacterial ProteinsSerine EndopeptidasesBhpABorreliaBtpAHtrAoxidative stressrelapsing feverrelapsing fever borrelia

Identifiers

PMID31456953
PMCPMC6700303
OpenAlexW2965773600

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.