ArticleBiomedical engineering letters2019
A multiscale Mueller polarimetry module for a stereo zoom microscope.
Article in Biomedical engineering letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- Label-free differentiation of classical and hypermobile Ehlers-Danlos syndromes using Mueller matrix polarimetry.Biophotonics discovery · 2026Article
- Machine learning-based prediction of luminal breast cancer subtypes using polarised light microscopy.British journal of cancer · 2025Article
- Machine learning based local recurrence prediction in colorectal cancer using polarized light imaging.Journal of biomedical optics · 2024Article
- Characterizing colon cancer stages through optical polarimetry-assisted digital staining.Lasers in medical science · 2024Article
- Mueller matrix polarization parameters correlate with local recurrence in patients with stage III colorectal cancer.Scientific reports · 2023Article
- Comparative study of the influence of imaging resolution on linear retardance parameters derived from the Mueller matrix.Biomedical optics express · 2021Article
- Photon mayhem: new directions in diagnostic and therapeutic photomedicine.Biomedical engineering letters · 2019Article
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
Abstract
Mueller polarimetry is a quantitative polarized light imaging modality that is capable of label-free visualization of tissue pathology, does not require extensive sample preparation, and is suitable for wide-field tissue analysis. It holds promise for selected applications in biomedicine, but polarimetry systems are often constrained by limited end-user accessibility and/or long-imaging times. In order to address these needs, we designed a multiscale-polarimetry module that easily couples to a commercially available stereo zoom microscope. This paper describes the module design and provides initial polarimetry imaging results from a murine preclinical breast cancer model and human breast cancer samples. The resultant polarimetry module has variable resolution and field of view, is low-cost, and is simple to switch in or out of a commercial microscope. The module can reduce long imaging times by adopting the main imaging approach used in pathology: scanning at low resolution to identify regions of interest, then at high resolution to inspect the regions in detail. Preliminary results show how the system can aid in region of interest identification for pathology, but also highlight that more work is needed to understand how tissue structures of pathological interest appear in Mueller polarimetry images across varying spatial zoom scales.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.