Evidence map›Paper›PMID 31456855›Full record

ReviewNuclear medicine and molecular imaging2019

Measurement of Tumor Pressure and Strategies of Imaging Tumor Pressure for Radioimmunotherapy.

Hyeon-Gi Kim, A Ram Yu, Jae Joon Lee, Yong-Jin Lee, Sang Moo Lim, Jin Su Kim

Open access · hybridAbstract readReview
In one paragraph

Review in Nuclear medicine and molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. [Hepatocellular Carcinoma-Derived Exosomes: Key Players in Intercellular Communication Within the Tumor Microenvironment].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Hyeon-Gi Kim1Division of RI application, Korea Institute of Radiological and Medical Sciences & Radiological and Medico-Oncological Sciences, University of Science and Technology (UST), 75 Nowon-Gil, Gongneung-Dong, Nowon-Gu, Seoul, 01812 South Korea.
A Ram Yu2Laboratory Animal center, Osong Medical Innovation Foundation, Cheongju, Chungbuk South Korea.
Jae Joon Lee2Laboratory Animal center, Osong Medical Innovation Foundation, Cheongju, Chungbuk South Korea.
Yong-Jin Lee1Division of RI application, Korea Institute of Radiological and Medical Sciences & Radiological and Medico-Oncological Sciences, University of Science and Technology (UST), 75 Nowon-Gil, Gongneung-Dong, Nowon-Gu, Seoul, 01812 South Korea.
Sang Moo Lim1Division of RI application, Korea Institute of Radiological and Medical Sciences & Radiological and Medico-Oncological Sciences, University of Science and Technology (UST), 75 Nowon-Gil, Gongneung-Dong, Nowon-Gu, Seoul, 01812 South Korea.
Jin Su Kim1Division of RI application, Korea Institute of Radiological and Medical Sciences & Radiological and Medico-Oncological Sciences, University of Science and Technology (UST), 75 Nowon-Gil, Gongneung-Dong, Nowon-Gu, Seoul, 01812 South Korea.ORCID 0000-0001-8965-9538
Korea Institute of Radiological and Medical Sciences · KROsong Medical Innovation Foundation · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumor interstitial pressure is a fundamental feature of cancer biology. Elevation in tumor pressure affects the efficacy of cancer treatment and results in the heterogenous intratumoral distribution of drugs and macromolecules. Monoclonal antibodies (mAb) play a prominent role in cancer therapy and molecular nuclear imaging. Therapy using mAb labeled with radionuclides-also known as radioimmunotherapy (RIT)-is an effective form of cancer treatment. RIT is clinically effective for the treatment of lymphoma and other blood cancers; however, its clinical use for solid tumor was limited because their high interstitial pressure prevents mAb from penetrating into the tumor. This pressure can be decreased using anti-cancer drugs or additional external therapy. In this paper, we reviewed the intratumoral pressure using direct tumor-pressure measurement strategies, such as the wick-in-needle and pressure catheter transducer method, and indirect tumor-pressure measurement strategies via magnetic resonance.

Indexed as

ADCMonoclonal antibodyRadioimmunotherapyTumor pressure

Identifiers

PMID31456855
PMCPMC6694369
OpenAlexW2949471445

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.