Evidence map›Paper›PMID 31456732›Full record

ArticleFrontiers in neurology2019

Total and Regional White Matter Lesions Are Correlated With Motor and Cognitive Impairments in Carriers of the

Darren R Hocking, Danuta Z Loesch, Nicholas Trost, Minh Q Bui, Eleanor Hammersley, David Francis, Flora Tassone, Elsdon Storey

Abstract read
In one paragraph

Article in Frontiers in neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Cognitive dysfunction in women with theJournal of Alzheimer's disease : JAD · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. FMR1 CGG Repeats and Stress Influence Self-Reported Cognitive Functioning in Mothers.American journal on intellectual and developmental disabilities · 2023
    Article
  7. Article
  8. Cerebral Microbleeds in Fragile X-Associated Tremor/Ataxia Syndrome.Movement disorders : official journal of the Movement Disorder Society · 2021
    Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Darren R HockingDevelopmental Neuromotor and Cognition Lab, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia.
Danuta Z LoeschSchool of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia.
Nicholas TrostDepartment of Radiology, St. Vincent's Hospital Melbourne, Fitzroy, VIC, Australia.
Minh Q BuiCentre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Melbourne, VIC, Australia.
Eleanor HammersleyDevelopmental Neuromotor and Cognition Lab, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia.
David FrancisVCGS Cytogenetics Laboratory, Murdoch Children's Research Institute, Royal Children's Hospital, Melbourne, VIC, Australia.
Flora TassoneDepartment of Biochemistry and Molecular Medicine, University of California, Davis, Davis, CA, United States.
Elsdon StoreyDepartment of Medicine (Neuroscience), Central Clinical School, Monash University, Melbourne, VIC, Australia.

Funding

GENOTYPE/PHENOTYPE RELATIONSHIPS IN FRAGILE X FAMILIESR01HD036071 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI PAUL J HAGERMAN, RANDI J. HAGERMAN · 1998 to 2026
$13.8M
NICHD NIH HHS R01 HD036071
6 · The paper itself

Abstract

This study explores the relationships between hemispheric and cerebellar white matter lesions and motor and cognitive impairments in male carriers of Fragile-X Mental Retardation 1 (

Indexed as

cognitive impairmentFMR1 premutation carriersFXTASmotor scoresMRIwhite matter hyperintensities

Identifiers

PMID31456732
PMCPMC6700239

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.