ArticleFrontiers in physiology2019
The Effects of Restriction Pressures on the Acute Responses to Blood Flow Restriction Exercise.
Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06762912 (The Short-term Effect of Low-load Resistance Training with Blood-flow Restriction on Somatosensory-evoked Potentials in Healthy Young Adults - a Randomized Crossover Trial), which is not on this map. Cited by 36 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Short-term Effect of Low-load Resistance Training with Blood-flow Restriction on Somatosensory-evoked Potentials in Healthy Young Adults - a Randomized Crossover Trial
Who cites it
36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 76 citations in OpenAlex.
- The immediate effects of blood flow restriction training on upper limb muscle strength and fatigue level: a meta-analysis.Frontiers in physiology · 2025Pooled it
- The Effects of Blood Flow Restriction in Patients Undergoing Knee Surgery: A Systematic Review and Meta-analysis.The American journal of sports medicine · 2022Pooled it
- Low-Load Blood-Flow Restriction Exercise to Failure and Nonfailure and Myoelectric Activity: A Meta-Analysis.Journal of athletic training · 2022Pooled it
- A Systematic Review and Meta-Analysis on Neural Adaptations Following Blood Flow Restriction Training: What We Know and What We Don't Know.Frontiers in physiology · 2020Pooled it
- Blood flow restriction exacerbates muscle deoxygenation and fatigue during sport climbing specific finger flexors resistance training.European journal of applied physiology · 2026Trial
- Effects of different arterial occlusion pressures during blood flow restriction exercise on muscle damage: a single-blind randomized controlled trial.Scientific reports · 2025Trial
- Trial
- The Reliability and Validity of Manual Palpation to Assess Lower Limb Arterial Occlusion Pressure in Older Adults, for Application in Blood Flow Restriction Exercise.European journal of sport science · 2026Article
- Acute Effects of Low-Load Blood Flow Restriction Exercise on Vastus Lateralis Electromyographic Activity in Healthy Young Adults: A Pilot Randomized Study.Journal of functional morphology and kinesiology · 2026Article
- Review
- Does exercising bilaterally require measuring bilaterally? Bilateral versus unilateral tourniquet cuff inflation during measurement of arterial occlusion pressure: considerations for blood flow restriction exercise.Frontiers in physiology · 2026Article
- Pressure point: blood flow restriction exercise and the pain paradox in musculoskeletal injury and persistent pain populations-a narrative review.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Pressure prescription in blood flow restriction training: evaluating the role of arterial occlusion pressure.Frontiers in sports and active living · 2026Review
- Acute neuromuscular and metabolic responses to complex training with blood flow restriction: effects of arterial occlusion pressure on post-activation performance enhancement.Frontiers in physiology · 2026Article
- The effect of aerobic exercise with blood flow restriction on substrate utilization and energy expenditure.Frontiers in sports and active living · 2026Article
- Cold Compression and Ischemic Preconditioning With Ice Therapy Enhance Muscle Recovery and Functionality Post-Exercise: A Randomized Study.Annals of rehabilitation medicine · 2025Article
- Perceptual and Metabolic Responses During Resistance Training Sessions: Comparing Low-Load Plus Blood Flow Restriction with High-Load Plans.Sports (Basel, Switzerland) · 2025Article
- Acute effects of blood flow restriction training at various arterial occlusion pressures on muscle activation, blood lactate responses, and RPE in healthy adult males.Frontiers in physiology · 2025Article
- The effects of blood flow restriction training on post activation potentiation and fatigue level: systematic review with meta-analysis.Frontiers in physiology · 2025Review
- Impact of Five Weeks of Strengthening Under Blood Flow Restriction (BFR) or Supplemental Oxygen Breathing (Normobaric Hyperoxia) on the Medial Gastrocnemius.Journal of functional morphology and kinesiology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeNo current guidelines or recommendations exist informing the selection of restriction pressure during blood flow restriction exercise (BFRE). Moreover, the effects of specific relative restriction pressures on the acute muscle, metabolic and cardiopulmonary responses to BFRE are unclear. The purpose of this study was to characterize these acute responses at different levels of restriction pressure.
methodsParticipants (
resultsFor the LL and B-40 trials, most measures remained constant. However, for the B-60 and B-80 trials, significant fatigue was demonstrated by a reduction in MVC torque across the trial (
conclusionWe demonstrate graded/progressive acute responses with increasing applied pressure during BFRE, from which we speculate that an effective minimum "threshold" around 60% LOP may be necessary for BFRE to be effective with training. While these data provide some insight on the possible mechanisms by which BFRE develops skeletal muscle size and strength when undertaken chronically across a training program, the outcomes of chronic training programs using different levels of applied restriction pressures remain to be tested. Overall, the present study recommends 60-80% LOP as a suitable "minimum" BFRE pressure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.