ArticleInternational journal of nanomedicine2019
Comparative study on antidiabetic, cytotoxicity, antioxidant and antibacterial properties of biosynthesized silver nanoparticles using outer peels of two varieties of
Article in International journal of nanomedicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 68 citations in OpenAlex.
- Unlocking the Therapeutic Efficacies of Silver Nanoparticles Derived Using the Plant-Based Aqueous Extract: A Comprehensive Review.Applied biochemistry and biotechnology · 2026Review
- Evaluation of quality characteristics, antioxidant activity, functional groups of sweet potato by-products and their usage in sandwich bread processing.Food chemistry: X · 2026Article
- Eco-Friendly Synthesis and Characterization ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Anticancer activity of curcumin loaded hybrid system of silver-amine functionalized silica nanoparticles.Scientific reports · 2026Article
- The potential of Eco-friendly synthesis of multifunctional ZnO-CuO nanocomposites using Mentha longifolia extract for their biomedical applications.Journal of materials science. Materials in medicine · 2025Article
- Biosynthesized Silver Nanoparticles and Their Antidiabetic Potential.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Antidiabetic Activity of Silver Nanoparticles Biosynthesized withPharmaceuticals (Basel, Switzerland) · 2025Article
- The potential protective effects of curcumin on the diabetic ovary: Experimental and molecular approaches.Histology and histopathology · 2025Review
- Unveiling the Role of Sweet Potato Root in Skin Health: A New Approach to Collagen Synthesis and Rejuvenation.Food science & nutrition · 2025Review
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- Plant-Based Diets and Phytochemicals in the Management of Diabetes Mellitus and Prevention of Its Complications: A Review.Nutrients · 2024Review
- Ocimum basilicum seed-mediated green synthesis of silver nanoparticles: characterization and evaluation of biological properties.Discover nano · 2024Article
- Sputtering-Deposited Ultra-Thin Ag-Cu Films on Non-Woven Fabrics for Face Masks with Antimicrobial Function and Breath NOMaterials (Basel, Switzerland) · 2024Article
- The Potential of the Flavonoid Content ofMetabolites · 2023Review
- Article
- A Critical Review of the Antimicrobial and Antibiofilm Activities of Green-Synthesized Plant-Based Metallic Nanoparticles.Nanomaterials (Basel, Switzerland) · 2022Review
- Biomimetic Synthesis of Silver Nanoparticles Using Ethyl Acetate Extract ofMicroorganisms · 2022Article
- Eco-friendly synthesis of silver nanoparticles from the whole plant ofSaudi journal of biological sciences · 2020Article
- A Brief Overview on Antioxidant Activity Determination of Silver Nanoparticles.Molecules (Basel, Switzerland) · 2020Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background
methodsIn this study, using the outer peel of two varieties of Ib : Korean red skin sweet potato and Korean pumpkin sweet potato, silver nanoparticles (AgNPs) were synthesized (termed Ib1-AgNps and Ib2-AgNps), respectively. Characterization of Ib1-AgNPs and Ib2-AgNPs was carried out through scanning electron microscopy, Fourier-transform infrared (FT-IR) spectroscopy, energy-dispersive X-ray analysis, X-ray powder diffraction and UV-Vis spectroscopy. Further, the bio-potential of the synthesized AgNPs was investigated by antidiabetic (α-glucosidase assay), antioxidant (free radical scavenging assays), antibacterial (disc diffusion method) and cytotoxicity assays (cell viability against HepG2 cells).
resultsFT-IR spectroscopy revealed the contribution of bioactive compounds existing in Ib1 and Ib2 extracts, in the biosynthesis and equilibrium of the AgNPs. Although the Ib2-AgNPs had a higher atomic percentage of Ag in comparison with Ib1-AgNPs, in the antidiabetic assay, the inhibition percentage of α-glucosidase was higher for AgNPs of Ib1 than Ib2, at all three concentrations examined. From the cytotoxicity results, HepG2 cancer cells were more sensitive to the Ib1-AgNPs in comparison to the Ib2-AgNPs-treated HepG2 cells. The antioxidant prospective was higher in Ib2-AgNPs than Ib1-AgNPs. Moreover, the Ib2-AgNPs showed inhibitory action against all five tested pathogenic bacteria, producing an inhibition zone of 8.74-11.52 mm while Ib1-AgNPs had an inhibitory effect on four of them, with an 8.67-11.23 (mm) inhibition zone.
conclusionsOverall, the results concluded that the Ib2-AgNPs exhibited relatively higher functional activity than Ib1-AgNPs, which might be credited to the greater abundance of bioactive compounds existing in Ib2 extract that acted as reducing as well as capping agents in the synthesis of Ib2-AgNPs. Overall, the current study highlights a novel cost-effective and eco-friendly AgNPs synthesis using food waste peels with biocompatibility and could be potentially utilized in biomedical and pharmaceutical industries.
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