ArticlePsychological medicine2020
Timing of menarche and self-harm in adolescence and adulthood: a population-based cohort study.
Article in Psychological medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Phenols, Parabens, Phthalates and Puberty: a Systematic Review of Synthetic Chemicals Commonly Found in Personal Care Products and Girls' Pubertal Development.Current environmental health reports · 2022Pooled it
- A Systematic Literature Review of Factors Affecting the Timing of Menarche: The Potential for Climate Change to Impact Women's Health.International journal of environmental research and public health · 2020Pooled it
- Modern Determinants of Earlier Menarche and Mental Health: A Translational Review for Clinicians.Children (Basel, Switzerland) · 2026Review
- Early Pubertal Timing, Suicidality, and Self-Injurious Behaviors in Preadolescents: Evidence for Concurrent and Emergent Risk Prediction.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Article
- Early menarche is associated with disordered eating-results from a National Youth Survey.Pediatric research · 2025Article
- Associations of menstrual characteristics with non-suicidal self-injury: results from six universities in China.BMC public health · 2025Article
- Factors associated with chronic depressive symptoms across adolescence and young adulthood: a UK birth cohort study.Epidemiology and psychiatric sciences · 2024Article
- Metabolome-wide Mendelian randomization for age at menarche and age at natural menopause.Genome medicine · 2024Article
- Early puberty: a review on its role as a risk factor for metabolic and mental disorders.Frontiers in pediatrics · 2024Review
- Pubertal timing: A life course pathway linking early life risk to adulthood cardiometabolic health.PloS one · 2024Article
- Misophonia, self-harm and suicidal ideation.PCN reports : psychiatry and clinical neurosciences · 2023Article
- The effects of obesity on the menstrual cycle.Current problems in pediatric and adolescent health care · 2022Article
- Use of electronic vaping products and mental health among adolescent high school students in the United States: The moderating effect of sex.Journal of psychiatric research · 2022Article
- The Use of a Two-Phase Online Delphi Panel Methodology to Inform the Concurrent Development of a School-Based Ovulatory Menstrual Health Literacy Intervention and Questionnaire.Frontiers in global women's health · 2022Article
- Self-harm in children 12 years and younger: characteristics and outcomes based on the Multicentre Study of Self-harm in England.Social psychiatry and psychiatric epidemiology · 2022Article
- Advances in Research on Adolescent Suicide and a High Priority Agenda for Future Research.Journal of research on adolescence : the official journal of the Society for Research on Adolescence · 2021Review
- Machine Learning Assessment of Early Life Factors Predicting Suicide Attempt in Adolescence or Young Adulthood.JAMA network open · 2021Article
- Suicide assessment and treatment in pediatric primary care settings.Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc · 2020Article
- Pubertal timing and self-harm: a prospective cohort analysis of males and females.Epidemiology and psychiatric sciences · 2020Article
- Understanding When and Why Some Adolescent Girls Attempt Suicide: An Emerging Framework Integrating Menstrual Cycle Fluctuations in Risk.Child development perspectives · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundPrevious studies of pubertal timing and self-harm are limited by subjective measures of pubertal timing or by the conflation of self-harm with suicide attempts and ideation. The current study investigates the association between an objective measure of pubertal timing - age at menarche - and self-harm with and without suicidal intent in adolescence and adulthood in females.
methodBirth cohort study based on 4042 females from the Avon Longitudinal Study of Parents and Children (ALSPAC). Age at menarche was assessed prospectively between ages 8 and 17 years. Lifetime history of self-harm was self-reported at ages 16 and 21 years. Associations between age at menarche and self-harm, both with and without suicidal intent, were examined using multivariable logistic regression.
resultsLater age at menarche was associated with a lower risk of lifetime self-harm at age 16 years (OR per-year increase in age at menarche 0.87; 95% CI 0.80-0.95). Compared with normative timing, early menarche (<11.5 years) was associated with an increased risk of self-harm (OR 1.31, 95% CI 1.04-1.64) and later menarche (>13.8 years) with a reduced risk (OR 0.74, 95% CI 0.58-0.93). The pattern of association was similar at age 21 years (OR per-year increase in age at menarche 0.92, 95% CI 0.85-1.00). There was no strong evidence for a difference in associations with suicidal v. non-suicidal self-harm.
conclusionsRisk of self-harm is higher in females with early menarche onset. Future research is needed to establish whether this association is causal and to identify potential mechanisms.
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