ArticleCurrent HIV research2019
Frailty among HIV-1 Infected Adults under Antiretroviral Therapy in Indonesia.
Article in Current HIV research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Exploring frailty in the context of HIV and aging in Kazakhstan: findings from a pilot cross-sectional study.BMC public health · 2026Article
- Frailty among adult people living with HIV in Tanzania: a single-centred hospital-based cross-sectional study.BMJ public health · 2026Article
- Frailty assessment: An emerging concept in aged People Living with HIV (PLHIV).Journal of family medicine and primary care · 2023Article
- Article
- The impact of frailty and illness perceptions on quality of life among people living with HIV in Greece: A network analysis.PloS one · 2023Article
- Prevalence of Frailty and Prefrailty in People With Human Immunodeficiency Virus Aged 50 or Older: A Systematic Review and Meta-Analysis.Open forum infectious diseases · 2022Article
- Low Quality of Life, Falls, and Pre-Frailty are Associated with Depressive Symptoms in Virologically Suppressed PLWHIV in Salvador, Brazil.AIDS and behavior · 2022Article
- Risk of Falls in HIV-Infected Patients on Antiretroviral Therapy and Its Associated Factors.HIV/AIDS (Auckland, N.Z.) · 2022Article
- Assessment, prevalence, and correlates of frailty among middle-aged adults with HIV in rural Uganda.Journal of neurovirology · 2021Article
- Suicidal ideation, psychopathology and associated factors among HIV-infected adults in Indonesia.BMC psychiatry · 2020Article
- Physical Function and Frailty in HIV.Topics in antiviral medicineArticle
- Prevalence of Frailty Phenotypes in Older People Living with HIV: A Cross-Sectional Study from Brazil.Journal of the International Association of Providers of AIDS CareArticle
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5 authors.
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Abstract
backgroundIncreasing age of HIV-1 infected population brought about the risk of frailty as comorbidity, whose prevalence is higher in low and middle-income countries (LMICs). Indonesia as an LMIC also bears a major burden of HIV-1 epidemic with a similarly aging population, but the prevalence of frailty and its predictors are unknown.
objectivesTo identify the prevalence of frailty and analyze its associated factors, among HIV-1 infected adults under antiretroviral therapy in Indonesia.
methodsA cross-sectional study was conducted among HIV-infected individuals with inclusion criteria of age ≥30 years old and underwent ART for at least 6 months. The main assessment was done using Fried's frailty phenotype score, which categorizes subjects into non-frail, pre-frail, or frail. Factors associated with frailty were characterized and multiple logistic regression analysis was performed.
resultsA total of 164 subjects were recruited; male subjects were 118 (72%), the median age was 40.5 years old, and the median CD4 nadir was 53 cells/μl. Frailty was identified among 90 (54.9%) subjects with 84 (51.2%) identified as pre-frail and 6 (3.7%) as frail, with dominant frailty phenotype was weakness in grip strength. The multivariate model showed that depression was the only factor significantly correlated with pre-frailty and frailty (OR 2.14; 95% CI 1.04-4.43, p=0.036).
conclusionFrailty is a common occurrence among HIV-infected patients under ART, with depression as an independent predictive factor.
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