Evidence map›Paper›PMID 31456469›Full record

ArticleNutrition and health2019

The malnutrition in polytrauma patients (MaPP) study: Research protocol.

Suzan Dijkink, Karien Meier, Pieta Krijnen, D Dante Yeh, George C Velmahos, M Sesmu Arbous, Ali Salim, Jochem M Hoogendoorn, Inger B Schipper

Abstract readClinical Trial Protocol
In one paragraph

Article in Nutrition and health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Observational
  2. Observational
  3. Observational
  4. Prevalence, incidence, and complications of malnutrition in severely injured patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Observational
  5. The correlation of CT-derived muscle density, skeletal muscle index, and visceral adipose tissue with nutritional status in severely injured patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  6. Article
  7. Albumin: a comprehensive review and practical guideline for clinical use.European journal of clinical pharmacology · 2024
    Review
  8. Hypoalbuminemia: incidence and its impact on acute respiratory distress syndrome and 28-day outcome in trauma patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Suzan DijkinkDepartment of Surgery, Leiden University Medical Center, The Netherlands.ORCID https://orcid.org/0000-0002-8191-4247
Karien MeierDepartment of Surgery, Leiden University Medical Center, The Netherlands.
Pieta KrijnenDepartment of Surgery, Leiden University Medical Center, The Netherlands.
D Dante YehRyder Trauma Center, DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Florida, USA.
George C VelmahosDivision of Trauma, Emergency Surgery, and Surgical Critical Care, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.
M Sesmu ArbousDepartment of Intensive Care, Leiden University Medical Center Leiden, The Netherlands.
Ali SalimDepartment of Surgery, Division of Trauma, Burn and Surgical Critical Care, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Jochem M HoogendoornDepartment of General Surgery, Haaglanden Medical Center Westeinde, The Hague, The Netherlands.
Inger B SchipperDepartment of Surgery, Leiden University Medical Center, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolytrauma patients are at risk of considerable harm from malnutrition due to the metabolic response to trauma. However, there is little knowledge of (the risk of) malnutrition and its consequences in these patients. Recognition of sub-optimally nourished polytrauma patients and their nutritional needs is crucial to prevent complications and optimize their clinical outcomes.

aimThe primary objective is to investigate whether polytrauma patients admitted to the Intensive Care Unit (ICU) who have or develop malnutrition have a higher complication rate than patients who are and remain well nourished. Secondary objectives are to determine the prevalence of pre-existent and in-hospital acquired malnutrition in these patients, to assess the association between malnutrition and long-term outcomes, and to determine the association between serum biomarkers (albumin and pre-albumin) and malnutrition.

methodsThis international observational prospective cohort study will be performed at three Level-1 trauma centers in the United States and two Level-1 centers in the Netherlands. Adult polytrauma patients (Injury Severity Score ≥16) admitted to the ICU of one of the participating centers directly from the Emergency Department are eligible for inclusion. Nutritional status and risk of malnutrition will be assessed using the Subjective Global Assessment (SGA) scale and Nutritional Risk in Critically Ill (NUTRIC) score, respectively. Nutritional intake, biomarkers and complications will be collected daily. Patients will be followed up to one year after discharge for long-term outcomes.

conclusionsThis international prospective cohort study aims to gain more insight into the effect and consequences of malnutrition in polytrauma patients admitted to the ICU.

Indexed as

MalnutritionMultiple TraumaNutritional StatusOutcome and Process Assessment, Health CareAdultBiomarkersEnergy IntakeGlasgow Outcome ScaleHumansInjury Severity ScoreIntensive Care UnitsNetherlandsNutritional SupportObservational Studies as TopicProspective StudiesProtein DeficiencyBiomarkerscritical caremulticenternutritionnutritional statusoutcomesTrauma

Identifiers

PMID31456469
PMCPMC6900577

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.