Evidence map›Paper›PMID 31456412›Full record

ArticleAIDS research and human retroviruses

Harvard HIV and Aging Workshop: Perspectives and Priorities from Claude D. Pepper Centers and Centers for AIDS Research.

Monty Montano, Shalender Bhasin, Richard T D'Aquila, Kristine M Erlandson, William J Evans, Nicholas T Funderburg, Amy Justice, Lishomwa C Ndhlovu, Bisola Ojikutu, Marco Pahor and 11 more

Open access · greenAbstract read
In one paragraph

Article in AIDS research and human retroviruses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 17 institutions in 1 country.

Monty MontanoBoston Pepper OAIC, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Shalender BhasinBoston Pepper OAIC, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Richard T D'AquilaFeinberg School of Medicine, Northwestern University, Chicago, Illinois.
Kristine M ErlandsonDivision of Infectious Disease, University of Colorado, Aurora, Colorado.
William J EvansDepartment of Nutritional Sciences and Toxicology, University of California, Berkeley, California.
Nicholas T FunderburgDivision of Medical Laboratory Science, School of Health and Rehabilitation Sciences, Ohio State University, Columbus, Ohio.
Amy JusticeDepartment of Medicine, Yale University School of Medicine, New Haven, Connecticut.
Lishomwa C NdhlovuDepartment of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii.
Bisola OjikutuDivision of Global Health Equity, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Marco PahorInstitute on Aging, Department of Aging and Geriatric Research, College of Medicine, University of Florida, Gainesville, Florida.
Savita PahwaDepartment of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, Florida.
Alice S RyanDivision of Gerontology and Geriatric Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland.
Jennifer SchrackDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Michael B SchultzDepartment of Genetics, Paul F. Glenn Labs for the Biology of Aging, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
Paola SebastianiDepartment of Biostatistics, Boston University, Boston, Massachusetts.
David A SinclairDepartment of Genetics, Paul F. Glenn Labs for the Biology of Aging, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts.
Julia TrippHarvard University Center for AIDS Research, Cambridge, Massachusetts.
Bruce WalkerRagon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts.
Julie A WomackVA Connecticut Healthcare System, West Haven, Connecticut.
Raymond YungDivision of Geriatric and Palliative Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
R Keith ReevesRagon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts.
Brigham and Women's Hospital · USHebrew SeniorLife · USRagon Institute of MGH, MIT and Harvard · USBoston University · USGeriatric Research Education and Clinical Center · USHarvard University · USInstitute on Aging · USJohns Hopkins University · USNorthwestern University · USThe Ohio State University · USUniversity of California, Berkeley · USUniversity of Colorado Denver · USUniversity of Hawaiʻi at Mānoa · USUniversity of Miami · USUniversity of Michigan–Ann Arbor · USVA Connecticut Healthcare System · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Gehan Devendra · 2017 to 2026
$59.5M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Neil Alexander · 2004 to 2026
$29.2M
University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
University of Florida Older Americans Independence Center (OAIC)P30AG028740 · NIA · UNIVERSITY OF FLORIDA · PI Peihua Qiu · 2007 to 2026
$22.8M
Uncovering the Human SecretomeDP1AG058605 · NIA · HARVARD MEDICAL SCHOOL · PI SINCLAIR, DAVID A. · 2017 to 2021
$5.9M
Role of Sgs1 DNA helicase in telomere maintenanceR01AG019719 · NIA · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI SINCLAIR, DAVID A. · 2001 to 2022
$5.3M
SIRT1 as a regulator of health and lifespan of mammalsR37AG028730 · NIA · HARVARD MEDICAL SCHOOL · PI SINCLAIR, DAVID A. · 2012 to 2021
$4.1M
Antigen-Specific NK Cell Memory Against SIV and HIV VaccinesR01AI120828 · NIAID · DUKE UNIVERSITY · PI REEVES, ROGER KEITH · 2017 to 2020
$3.5M
Mechanisms of innate modulation of SIV reservoirs and opportunistic disease in the oral cavityR01DE026014 · NIDCR · BETH ISRAEL DEACONESS MEDICAL CENTER · PI REEVES, ROGER KEITH · 2016 to 2020
$3.4M
Monocytes and HIV CNS Reservoirs in Super Acute HIV InfectionR01MH104141 · NIMH · UNIVERSITY OF HAWAII AT MANOA · PI NDHLOVU, LISHOMWA C · 2014 to 2018
$3.2M
NCATS NIH HHS UL1 TR001863NIAID NIH HHS P30 AI094189NIAID NIH HHS R01 AI120828NIA NIH HHS DP1 AG058605NIA NIH HHS K01 AG048765NIA NIH HHS P30 AG024824NIA NIH HHS P30 AG028740NIA NIH HHS P30 AG028747NIA NIH HHS R01 AG019719NIA NIH HHS R37 AG028730NIDCR NIH HHS R01 DE026014NIDDK NIH HHS R01 DK100263NIMHD NIH HHS U54 MD007601NIMH NIH HHS R01 MH104141
6 · The paper itself

Abstract

People aging with HIV (PAWH) infection experience greater impairments in physical and cognitive function, in addition to higher rates of peripheral comorbid conditions (e.g., renal failure, diabetes, bone fracture, hypertension, cardiovascular disease, polypharmacy, and multimorbidity). While multifactorial drivers, including HIV infection itself, antiretroviral therapy-related toxicities, disparities in care, and biobehavioral factors, likely contribute, there remains an overarching question as to what are the relevant age-related mechanisms and models that could inform interventions that promote health span and life span in PAWH? This workshop was convened to hear from experts on the biology of aging and HIV researchers studying PAWH to focus on advancing investigations at the interface of HIV and Aging. In this study, we summarize the discussions from the Harvard Center for AIDS Research and Boston Claude D. Pepper cosponsored workshop on HIV and Aging, which took place in October 2018.

Indexed as

AgingAgedBiomedical ResearchCardiovascular DiseasesCognitionComorbidityCongresses as TopicFrail ElderlyGeriatricsHIV InfectionsHumansHypertensionMaleagingfrailtyHIVimmune activation

Identifiers

PMID31456412
PMCPMC6862961
OpenAlexW2970213074

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.