Evidence map›Paper›PMID 31456089›Full record

ArticleAnnals of biomedical engineering2020

In Vivo MRI Assessment of Blood Flow in Arteries and Veins from Head-to-Toe Across Age and Sex in C57BL/6 Mice.

A Colleen Crouch, Amos A Cao, Ulrich M Scheven, Joan M Greve

Open access · greenAbstract readComparative Study
In one paragraph

Article in Annals of biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
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  4. Liquid Metal Microrobots for Magnetically Guided Transvascular Navigation.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
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  9. Article
  10. Insights from Murine Studies on the Site Specificity of Atherosclerosis.International journal of molecular sciences · 2024
    Review
  11. Article
  12. Hemodynamic response to thermal stress varies with sex and age: a murine MRI study.International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 2022
    Article
  13. Article
  14. Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A Colleen CrouchMechanical Engineering, University of Michigan, 1049 Bonisteel Interdisciplinary Research Building, 2360 Bonisteel Boulevard, Ann Arbor, MI, 48109-2099, USA. accrouch@umich.edu.ORCID http://orcid.org/0000-0002-1194-4897
Amos A CaoBiomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
Ulrich M SchevenMechanical Engineering, University of Michigan, 1049 Bonisteel Interdisciplinary Research Building, 2360 Bonisteel Boulevard, Ann Arbor, MI, 48109-2099, USA.
Joan M GreveBiomedical Engineering, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · US

Funding

Training Program in Translational Cardiovascular Research and EntrepreneurshipT32HL125242 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MICHELE, DANIEL E · 2015 to 2024
$1.9M
NHLBI NIH HHS T32 HL125242NIH HHS T32-HL125242
6 · The paper itself

Abstract

Although widely used as a preclinical model for studying cardiovascular diseases, there is a scarcity of in vivo hemodynamic measurements of the naïve murine system in multiple arterial and venous locations, from head-to-toe, and across sex and age. The purpose of this study is to quantify cardiovascular hemodynamics in mice at different locations along the vascular tree while evaluating the effects of sex and age. Male and female, adult and aged mice were anesthetized and underwent magnetic resonance imaging. Data were acquired from four co-localized vessel pairs (carotid/jugular, suprarenal and infrarenal aorta/inferior vena cava (IVC), femoral artery/vein) at normothermia (core temperature 37 ± 0.2 °C). Influences of age and sex on average velocity differ by location in arteries. Average arterial velocities, when plotted as a function of distance from the heart, decrease nearly linearly from the suprarenal aorta to the femoral artery (adult and aged males: - 0.33 ± 0.13, R

Indexed as

Regional Blood FlowSex CharacteristicsAgingAnimalsArteriesFemaleMagnetic Resonance ImagingMaleMice, Inbred C57BLVeinsAgeArterialCardiovascularHemodynamicsMurineSexVenous

Identifiers

PMID31456089
PMCPMC6930323
OpenAlexW2970534630

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.