ArticleArchives of virology2019
Bovine coronavirus in Uruguay: genetic diversity, risk factors and transboundary introductions from neighboring countries.
Article in Archives of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- First Isolation of Bovine Coronavirus From Yanbian, China, and Analytical Validation of a SYBR Green I RT-qPCR Panel for Calf Diarrhea Viruses.Transboundary and emerging diseases · 2026Article
- A One Health approach to bovine coronavirus vaccine development, using LSDV as a live virus vector.Human vaccines & immunotherapeutics · 2025Article
- Brain invasion of bovine coronavirus: molecular analysis of bovine coronavirus infection in calves with severe pneumonia and neurological signs.Journal of veterinary science · 2024Article
- Article
- Article
- Development of an IgY-Based Treatment to Control Bovine Coronavirus Diarrhea in Dairy Calves.Viruses · 2023Article
- Advances in Bovine Coronavirus Epidemiology.Viruses · 2022Review
- Bovine Coronavirus Co-infection and Molecular Characterization in Dairy Calves With or Without Clinical Respiratory Disease.Frontiers in veterinary science · 2022Article
- Bovine Coronavirus Infects the Respiratory Tract of Cattle Challenged Intranasally.Frontiers in veterinary science · 2022Article
- Evaluation of low-cost viral concentration methods in wastewaters: Implications for SARS-CoV-2 pandemic surveillances.Journal of virological methods · 2021Article
- Assessment of Influential Factors for Scours Associated withAnimals : an open access journal from MDPI · 2021Article
- Seroprevalence of bovine coronavirus and factors associated with the serological status in dairy cattle in the western region of Thailand.Veterinary world · 2021Article
- Causes of neonatal calf diarrhea and mortality in pasture-based dairy herds in Uruguay: a farm-matched case-control study.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021Article
- Clinical and molecular aspects of veterinary coronaviruses.Virus research · 2021Review
- Bovine respiratory coronavirus enhances bacterial adherence by upregulating expression of cellular receptors on bovine respiratory epithelial cells.Veterinary microbiology · 2021Article
- Bovine Coronavirus and the Associated Diseases.Frontiers in veterinary science · 2021Review
- Bovine coronavirus in neonatal calf diarrhoea in Iran.Veterinary medicine and science · 2020Article
- Coronaviruses in cattle.Tropical animal health and production · 2020Review
- Dissecting Transcription Factor-Target Interaction in Bovine Coronavirus Infection.Microorganisms · 2020Article
- Phylogenetic Analyses of Rotavirus A from Cattle in Uruguay Reveal the Circulation of Common and Uncommon Genotypes and Suggest Interspecies Transmission.Pathogens (Basel, Switzerland) · 2020Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Bovine coronavirus (BCoV) is a recognized cause of severe neonatal calf diarrhea, with a negative impact on animal welfare, leading to economic losses to the livestock industry. Cattle production is one of the most important economic sectors in Uruguay. The aim of this study was to determine the frequency of BCoV infections and their genetic diversity in Uruguayan calves and to describe the evolutionary history of the virus in South America. The overall detection rate of BCoV in Uruguay was 7.8% (64/824): 7.7% (60/782) in dairy cattle and 9.5% (4/42) in beef cattle. The detection rate of BCoV in samples from deceased and live calves was 10.0% (6/60) and 7.6% (58/763), respectively. Interestingly, there was a lower frequency of BCoV detection in calves born to vaccinated dams (3.3%, 8/240) than in calves born to unvaccinated dams (12.2%, 32/263) (OR: 4.02, 95%CI: 1.81-8.90; p = 0.00026). The frequency of BCoV detection was higher in colder months (11.8%, 44/373) than in warmer months (1.5%, 3/206) (OR: 9.05, 95%CI: 2.77-29.53, p = 0.000013). Uruguayan strains grouped together in two different lineages: one with Argentinean strains and the other with Brazilian strains. Both BCoV lineages were estimated to have entered Uruguay in 2013: one of them from Brazil (95%HPD interval: 2011-2014) and the other from Argentina (95%HPD interval: 2010-2014). The lineages differed by four amino acid changes, and both were divergent from the Mebus reference strain. Surveillance should be maintained to detect possible emerging strains that can clearly diverge at the antigenic level from vaccine strains.
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