Evidence map›Paper›PMID 31455992›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2020

The influence of folic acid-induced acute kidney injury on cardiac function and redox status in rats.

Tomislav Nikolic, Dejan Petrovic, Stevan Matic, Tamara Nikolic Turnic, Jovana Jeremic, Katarina Radonjic, Ivan Srejovic, Vladimir Zivkovic, Stefani Bolevich, Sergey Bolevich and 1 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07013136 (Efficacy and Safety of Folic Acid on Acute Kidney Injury in Adults), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07013136 early_phase1not yet recruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy and Safety of Folic Acid on Acute Kidney Injury in Adults: A Feasibility Study

TypeinterventionalSponsorThe University of Hong KongRan2025 to 2027Enrolled90ConditionsAcute Kidney InjuryArmsFolic Acid 5 MG
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Folic acid-induced animal model of kidney disease.Animal models and experimental medicine · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Tomislav NikolicFaculty of Medical Sciences, Department of Internal medicine, University of Kragujevac, Kragujevac, Serbia. nikolic.s.tomislav@gmail.com.ORCID 0000-0003-3382-691X
Dejan PetrovicFaculty of Medical Sciences, Department of Internal medicine, University of Kragujevac, Kragujevac, Serbia.
Stevan MaticDepartment for Pathological Anatomical Diagnosis, Clinical Center "Kragujevac", Kragujevac, Serbia.
Tamara Nikolic TurnicFaculty of Medical Sciences, Department of Pharmacy, University of Kragujevac, Kragujevac, Serbia.
Jovana JeremicFaculty of Medical Sciences, Department of Pharmacy, University of Kragujevac, Kragujevac, Serbia.
Katarina RadonjicFaculty of Medical Sciences, Department of Pharmacy, University of Kragujevac, Kragujevac, Serbia.
Ivan SrejovicFaculty of Medical Sciences, Department of Physiology, University of Kragujevac, Kragujevac, Serbia.
Vladimir ZivkovicFaculty of Medical Sciences, Department of Physiology, University of Kragujevac, Kragujevac, Serbia.
Stefani BolevichRussian Federation, Department of Pathophysiology, 1st Moscow State Medical University IM Sechenov, Moscow, Russia.
Sergey BolevichRussian Federation, Department of Human Pathology, 1st Moscow State Medical University IM Sechenov, Moscow, Russia.
Vladimir JakovljevicFaculty of Medical Sciences, Department of Physiology, University of Kragujevac, Kragujevac, Serbia.
University of Kragujevac · RSSechenov University · RUClinical Centre of Kragujevac · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the influence of acute kidney injury caused by high doses of folic acid on cardiac function and markers of oxidative stress in serum and isolated rat heart. Isolated hearts of Wistar albino rats (divided into two groups: control and folic acid group) were perfused according to Langendorff technique at basal coronary perfusion pressure CPP of 70 cm H

Indexed as

Folic AcidAcute Kidney InjuryAnimalsCoronary CirculationHeartHeart RateHydrogen PeroxideKidneyMaleMyocardiumNitritesOxidation-ReductionOxidative StressRats, WistarSuperoxidesThiobarbituric Acid Reactive SubstancesFolic AcidHydrogen PeroxideNitritesSuperoxidesThiobarbituric Acid Reactive SubstancesAcute kidney injuryCardiac functionFolic acidOxidative stress

Identifiers

PMID31455992
OpenAlexW2970883350

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.