ArticleJournal of materials science. Materials in medicine2019
14-3-3ε protein-immobilized PCL-HA electrospun scaffolds with enhanced osteogenicity.
Article in Journal of materials science. Materials in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- 14-3-3γ Knockdown promotes matrix mineralization in human mesenchymal stromal cells.Cell death & disease · 2026Article
- Composite Hydrogels with Embedded Electrospun Fibers as Drug Delivery Systems.Gels (Basel, Switzerland) · 2025Review
- In vivo imaging of adipose-derived stem cell sheets on biodegradable nonwoven fabric using X-ray CT.Biomedical engineering online · 2024Article
- Versatility of 14-3-3 proteins and their roles in bone and joint-related diseases.Bone research · 2024Review
- 14-3-3ε: a protein with complex physiology function but promising therapeutic potential in cancer.Cell communication and signaling : CCS · 2024Review
- Electrohydrodynamic Techniques for the Manufacture and/or Immobilization of Vesicles.Polymers · 2023Review
- Bone-Metabolism-Related Serum microRNAs to Diagnose Osteoporosis in Middle-Aged and Elderly Women.Diagnostics (Basel, Switzerland) · 2022Article
- YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways.Cancer cell international · 2021Article
- M-keratin nano-materials create a mineralized micro-circumstance to promote proliferation and differentiation of DPSCs.Journal of materials science. Materials in medicine · 2020Article
- 14-3-3ε protein-loaded 3D hydrogels favor osteogenesis.Journal of materials science. Materials in medicine · 2020Article
- A Comprehensive Review of the Covalent Immobilization of Biomolecules onto Electrospun Nanofibers.Nanomaterials (Basel, Switzerland) · 2020Review
- Meta-analysis of proteomics data from osteoblasts, bone, and blood: Insights into druggable targets, active factors, and potential biomarkers for bone biomaterial design.Journal of tissue engineeringArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adipose-derived mesenchymal stem cells (ASCs) accelerate the osteointegration of bone grafts and improve the efficiency in the formation of uniform bone tissue, providing a practical and clinically attractive approach in bone tissue regeneration. In this work, the effect of nanofibrous biomimetic matrices composed of poly(ε-caprolactone) (PCL), nanometric hydroxyapatite (nHA) particles and 14-3-3 protein isoform epsilon on the initial stages of human ASCs (hASCs) osteogenic differentiation was investigated. The cells were characterized by flow cytometry and induction to differentiation to adipogenic and osteogenic lineages. The isolated hASCs were induced to differentiate to osteoblasts over all scaffolds, and adhesion and viability of the hASCs were found to be similar. However, the activity of alkaline phosphatase (ALP) as early osteogenic marker in the PCL-nHA/protein scaffold was four times higher than in PCL-nHA and more than five times than the measured in neat PCL.
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Registered trials
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