Observational studyScientific reports2019
Association between visual function and the integrity of residual ellipsoid zone in resolved central serous chorioretinopathy.
Observational study in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 38 citations in OpenAlex.
- Ultra-Wide-Field Optical Coherence Tomography Assessment of Choroidal Parameters in Central Serous Chorioretinopathy.Diagnostics (Basel, Switzerland) · 2026Article
- Early vitrectomy for myopic foveoschisis before foveal detachment.Eye (London, England) · 2026Article
- Detailed Outer Retinal Assessment in Parkinson's Disease Using Directional OCT.Investigative ophthalmology & visual science · 2026Article
- Article
- The outer nuclear layer changes in full-thickness macular holes according to the restoration of the outer retinal layer postoperatively.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Article
- Photoreceptor damage in pachychoroid pigment epitheliopathy.Eye (London, England) · 2025Article
- Evaluation of Reflectivities of RPE, ELM, EZ, and Their Relationship With Subretinal Fluid Properties in Central Serous Chorioretinopathy.Investigative ophthalmology & visual science · 2025Article
- OCT Biomarkers in Ocular CLN2 Disease in Patients Treated With Intraventricular Enzyme Replacement Therapy.Investigative ophthalmology & visual science · 2024Article
- In-Depth Analysis of Preoperative OCT Markers as Prognostic Factors for Lamellar Macular Holes and Epiretinal Membrane Foveoschisis.Ophthalmology. Retina · 2024Article
- Evaluation and comparison of microperimetry and optical coherence tomography findings in patients with Behçet uveitis.International ophthalmology · 2024Article
- Retinal sensitivity and fundus autofluorescence in adult-onset foveomacular vitelliform dystrophy.Scientific reports · 2023Article
- Prediction of visual impairment in retinitis pigmentosa using deep learning and multimodal fundus images.The British journal of ophthalmology · 2023Article
- Foveal microstructure and visual function in patients with lamellar macular hole, epiretinal membrane foveoschisis or macular pseudohole.Eye (London, England) · 2022Article
- Quantitative analysis of choroidal vasculature in central serous chorioretinopathy using ultra-widefield swept-source optical coherence tomography angiography.Scientific reports · 2022Article
- Structural-vascular-functional correlation in type 2 non-proliferative macular telangiectasia.International journal of retina and vitreous · 2022Article
- Assessment of Scleral Contour Changes in High Myopia by Optical Coherence Tomography.Korean journal of ophthalmology : KJO · 2022Article
- Clinical classification, visual outcomes, and optical coherence tomographic features of 48 patients with posterior sympathetic ophthalmia.Orphanet journal of rare diseases · 2022Article
- Trends in research related to ophthalmic microperimetry from 1992 to 2022: A bibliometric analysis and knowledge graph study.Frontiers in medicine · 2022Article
- Optical coherence tomography parameters as predictors of treatment response to a 577-nm subthreshold micropulse laser in chronic central serous chorioretinopathy.Lasers in medical science · 2021Article
- Assessment of macular function in patients with non-vascularized pigment epithelial detachment.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Central serous chorioretinopathy (CSC) usually resolves spontaneously; however, in some patients, it can be chronic and visual impairment remains even after resolution of the serous retinal detachment. The impaired photoreceptor cells often present with disrupted ellipsoid zone (EZ) on optical coherence tomography (OCT). In this study, the integrity of EZ was quantified by calculating the index of residual EZ, identified on binarized OCT images from 25 eyes of 23 patients with resolved CSC. To estimate residual EZ, integrity of residual EZ with the central horizontal line on the fovea (rEZc) and average integrity of residual EZ within 3 × 3-mm macular area (rEZave) were investigated. The interrater reliability of the method was assessed using the intraclass correlation coefficient (ICC). The relationship between LogMAR VA and age, central retinal thickness, central choroidal thickness, rEZc, and rEZave were evaluated using the linear mixed model. Retinal sensitivity was measured with the MP-3 microperimeter and similar analyses were iterated for mean retinal sensitivity (MS). ICC values were 0.938 with rEZc and 0.979 with rEZave. rEZc was significantly related to LogMAR VA (p = 0.039). rEZave was significantly related to MS (p < 0.001). These results suggested potential usefulness of residual EZ to predict visual function in resolved CSC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.